caa a22 4500 60545941X CHVBK 20210128100233.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00167-014-3014-5 doi (NATIONALLICENCE)springer-10.1007/s00167-014-3014-5 Variable bone mineral density reductions post-unicompartmental knee arthroplasty [Elektronische Daten] [Mahmut Tuncer, Rajesh Patel, Justin Cobb, Ulrich Hansen, Andrew Amis] Purpose: Radiolucencies are commonly observed in unicompartmental knee arthroplasty (UKA) patients within 1 year of arthroplasty. The objective of the study was to identify how the bone mineral density (BMD) changes up to 1 year post-arthroplasty. Methods: Dual X-ray absorptiometry scans were obtained from 11 UKA patients at 10days and 3, 6, and 12months post-surgery. Patients were scanned in both anteroposterior and lateral knee orientations. Results: Most subjects saw a large decline in BMD in the first 6months following surgery, followed by some recovery in bone mass. The biggest change occurred under the tibial intercondylar eminence, which decreased significantly by an average of 18% at 6 months and was 15% at 1 year. The average bone loss under the tibial tray was low; however, the bone loss at the anterior portion was higher with a significant average decrease of 14%. There was no change in BMD under the tibial keel. There was significant bone loss of 13% under the femoral component; the regions anterior and posterior to the central femoral implant peg both had significant bone loss of 14%. The bone response between patients was very variable, with some patients losing bone steadily, and others gaining it rapidly after an early fall. Conclusions: While the overall reduction in BMD under both components was low, it was significant and there was substantial individual variation superimposed on this. Improving our understanding of this response to surgery may impact on prosthesis survival. Level of evidence: Therapeutic study: case series with no comparison group, Level IV. The Author(s), 2014 Unicompartmental knee arthroplasty nationallicence UKA nationallicence Bone density changes nationallicence BMD nationallicence DXA nationallicence Tuncer Mahmut Department of Mechanical Engineering, Imperial College London, Exhibition Road, SW7 2AZ, London, UK aut Patel Rajesh Department of Musculoskeletal Surgery, Charing Cross Hospital, Imperial College London, W6 8RF, London, UK aut Cobb Justin Department of Musculoskeletal Surgery, Charing Cross Hospital, Imperial College London, W6 8RF, London, UK aut Hansen Ulrich Department of Mechanical Engineering, Imperial College London, Exhibition Road, SW7 2AZ, London, UK aut Amis Andrew Department of Mechanical Engineering, Imperial College London, Exhibition Road, SW7 2AZ, London, UK aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/8(2015-08-01), 2230-2236 0942-2056 23:8<2230 2015 23 167 https://doi.org/10.1007/s00167-014-3014-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-3014-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tuncer Mahmut Department of Mechanical Engineering, Imperial College London, Exhibition Road, SW7 2AZ, London, UK aut NATIONALLICENCE 700 1- Patel Rajesh Department of Musculoskeletal Surgery, Charing Cross Hospital, Imperial College London, W6 8RF, London, UK aut NATIONALLICENCE 700 1- Cobb Justin Department of Musculoskeletal Surgery, Charing Cross Hospital, Imperial College London, W6 8RF, London, UK aut NATIONALLICENCE 700 1- Hansen Ulrich Department of Mechanical Engineering, Imperial College London, Exhibition Road, SW7 2AZ, London, UK aut NATIONALLICENCE 700 1- Amis Andrew Department of Mechanical Engineering, Imperial College London, Exhibition Road, SW7 2AZ, London, UK aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/8(2015-08-01), 2230-2236 0942-2056 23:8<2230 2015 23 167