Less deep vein thrombosis due to transcutaneous fibular nerve stimulation in total knee arthroplasty: a randomized controlled trial

Verfasser / Beitragende:
[Masashi Izumi, Masahiko Ikeuchi, Koji Aso, Natsuki Sugimura, Yuko Kamimoto, Tetsuya Mitani, Tadashi Ueta, Takayuki Sato, Masataka Yokoyama, Tetsuro Sugiura, Toshikazu Tani]
Ort, Verlag, Jahr:
2015
Enthalten in:
Knee Surgery, Sports Traumatology, Arthroscopy, 23/11(2015-11-01), 3317-3323
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00167-014-3141-z  |2 doi 
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245 0 0 |a Less deep vein thrombosis due to transcutaneous fibular nerve stimulation in total knee arthroplasty: a randomized controlled trial  |h [Elektronische Daten]  |c [Masashi Izumi, Masahiko Ikeuchi, Koji Aso, Natsuki Sugimura, Yuko Kamimoto, Tetsuya Mitani, Tadashi Ueta, Takayuki Sato, Masataka Yokoyama, Tetsuro Sugiura, Toshikazu Tani] 
520 3 |a Purpose: It has been known for years that deep vein thrombi (DVT) start to develop during total joint arthroplasty. Previously, we reported effective prevention of venous stasis by transcutaneous electrical nerve stimulation (TENS). It is hypothesized that TENS might be a thromboprophylactic tool for the limb undergoing surgery. The purpose of this study is to clarify the clinical efficacy and safety of TENS in patients during total knee arthroplasty (TKA). Methods: Ninety patients undergoing primary TKA were involved and randomly allocated to the TENS or control group. In the TENS group, electrical stimulation of the common fibular nerve, which produced a brisk dorsiflexion of the ankle, was performed for the operated leg during surgery. In the control group, no electrical stimulation was applied. Serum D-dimer and soluble fibrin monomer complex (SFMC) levels were measured before surgery, immediately after surgery, and post-operative day (POD) 1. Ultrasonography was performed on POD 1. Results: Immediately after surgery, D-dimer and SFMC levels of each group were significantly lower in the TENS group compared with control (p<0.05). The incidence of DVT was 11% (five cases) in the TENS group while 31% (14 cases) in control (p=0.02). There were no adverse effects related to TENS. Conclusions: TENS during TKA showed significant effects on preventing DVT. Sustaining muscle pump activation during surgery prevented not only venous stasis, but also hypercoagulability of blood. Intraoperative TENS is a safe and novel strategy against early post-operative thromboembolism, which is difficult to be completed through existing prophylaxis after total joint arthroplasty. Level of evidence: Randomized controlled trial, Level I. 
540 |a Springer-Verlag Berlin Heidelberg, 2014 
690 7 |a Venous thromboembolism (VTE)  |2 nationallicence 
690 7 |a Deep vein thrombosis (DVT)  |2 nationallicence 
690 7 |a Pulmonary thromboembolism (PTE)  |2 nationallicence 
690 7 |a Transcutaneous electrical nerve stimulation (TENS)  |2 nationallicence 
690 7 |a Total knee arthroplasty (TKA)  |2 nationallicence 
690 7 |a Prevention  |2 nationallicence 
700 1 |a Izumi  |D Masashi  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
700 1 |a Ikeuchi  |D Masahiko  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
700 1 |a Aso  |D Koji  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
700 1 |a Sugimura  |D Natsuki  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
700 1 |a Kamimoto  |D Yuko  |u Department of Anesthesiology, Kochi University, Nankoku, Japan  |4 aut 
700 1 |a Mitani  |D Tetsuya  |u Department of Clinical Laboratory, Kochi University, Nankoku, Japan  |4 aut 
700 1 |a Ueta  |D Tadashi  |u Department of Clinical Laboratory, Kochi University, Nankoku, Japan  |4 aut 
700 1 |a Sato  |D Takayuki  |u Department of Cardiovascular Control, Kochi University, Nankoku, Japan  |4 aut 
700 1 |a Yokoyama  |D Masataka  |u Department of Anesthesiology, Kochi University, Nankoku, Japan  |4 aut 
700 1 |a Sugiura  |D Tetsuro  |u Department of Clinical Laboratory, Kochi University, Nankoku, Japan  |4 aut 
700 1 |a Tani  |D Toshikazu  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
773 0 |t Knee Surgery, Sports Traumatology, Arthroscopy  |d Springer Berlin Heidelberg  |g 23/11(2015-11-01), 3317-3323  |x 0942-2056  |q 23:11<3317  |1 2015  |2 23  |o 167 
856 4 0 |u https://doi.org/10.1007/s00167-014-3141-z  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00167-014-3141-z  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Izumi  |D Masashi  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ikeuchi  |D Masahiko  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Aso  |D Koji  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sugimura  |D Natsuki  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kamimoto  |D Yuko  |u Department of Anesthesiology, Kochi University, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Mitani  |D Tetsuya  |u Department of Clinical Laboratory, Kochi University, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ueta  |D Tadashi  |u Department of Clinical Laboratory, Kochi University, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sato  |D Takayuki  |u Department of Cardiovascular Control, Kochi University, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yokoyama  |D Masataka  |u Department of Anesthesiology, Kochi University, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sugiura  |D Tetsuro  |u Department of Clinical Laboratory, Kochi University, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tani  |D Toshikazu  |u Department of Orthopaedic Surgery, Kochi University, Oko-cho Kohasu, 783-8505, Nankoku, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Knee Surgery, Sports Traumatology, Arthroscopy  |d Springer Berlin Heidelberg  |g 23/11(2015-11-01), 3317-3323  |x 0942-2056  |q 23:11<3317  |1 2015  |2 23  |o 167