Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial

Verfasser / Beitragende:
[Lior Laver, Michael Carmont, Mark McConkey, Ezequiel Palmanovich, Eyal Yaacobi, Gideon Mann, Meir Nyska, Eugene Kots, Omer Mei-Dan]
Ort, Verlag, Jahr:
2015
Enthalten in:
Knee Surgery, Sports Traumatology, Arthroscopy, 23/11(2015-11-01), 3383-3392
Format:
Artikel (online)
ID: 605460779
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024 7 0 |a 10.1007/s00167-014-3119-x  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00167-014-3119-x 
245 0 0 |a Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial  |h [Elektronische Daten]  |c [Lior Laver, Michael Carmont, Mark McConkey, Ezequiel Palmanovich, Eyal Yaacobi, Gideon Mann, Meir Nyska, Eugene Kots, Omer Mei-Dan] 
520 3 |a Purpose: Syndesmotic sprains are uncommon injuries that require prolonged recovery. The influence of ultrasound-guided injections of platelet-rich plasma (PRP) into the injured antero-inferior tibio-fibular ligaments (AITFL) in athletes on return to play (RTP) and dynamic stability was studied. Methods: Sixteen elite athletes with AITFL tears were randomized to a treatment group receiving injections of PRP or to a control group. All patients followed an identical rehabilitation protocol and RTP criteria. Patients were prospectively evaluated for clinical ability to return to full activity and residual pain. Dynamic ultrasound examinations were performed at initial examination and at 6weeks post-injury to demonstrate re-stabilization of the syndesmosis joint and correlation with subjective outcome. Results: All patients presented with a tear to the AITFL with dynamic syndesmosis instability in dorsiflexion-external rotation, and larger neutral tibia-fibula distance on ultrasound. Early diagnosis and treatment lead to shorter RTP, with 40.8 (±8.9) and 59.6 (±12.0)days for the PRP and control groups, respectively (p=0.006). Significantly less residual pain upon return to activity was found in the PRP group; five patients (62.5%) in the control group returned to play with minor discomfort versus one patient in the treatment group (12.5%). One patient in the control group had continuous pain and disability and subsequently underwent syndesmosis reconstruction. Conclusions: Athletes suffering from high ankle sprains benefit from ultrasound-guided PRP injections with a shorter RTP, re-stabilization of the syndesmosis joint and less long-term residual pain. Level of evidence: II. 
540 |a Springer-Verlag Berlin Heidelberg, 2014 
690 7 |a Syndesmosis  |2 nationallicence 
690 7 |a Injections  |2 nationallicence 
690 7 |a Platelet-rich plasma  |2 nationallicence 
690 7 |a Ultrasound  |2 nationallicence 
690 7 |a Return to play  |2 nationallicence 
700 1 |a Laver  |D Lior  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
700 1 |a Carmont  |D Michael  |u Department of Trauma and Orthopaedic Surgery, Princess Royal Hospital, Telford, Shropshire, UK  |4 aut 
700 1 |a McConkey  |D Mark  |u Pacific Orthopaedics and Sports Medicine, North Vancouver, BC, Canada  |4 aut 
700 1 |a Palmanovich  |D Ezequiel  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
700 1 |a Yaacobi  |D Eyal  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
700 1 |a Mann  |D Gideon  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
700 1 |a Nyska  |D Meir  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
700 1 |a Kots  |D Eugene  |u Department of Radiology, Sports Medicine Unit, "Meir” Medical Center, Kfar-Saba, Israel  |4 aut 
700 1 |a Mei-Dan  |D Omer  |u Department of Sports Medicine, University of Colorado Hospitals, Boulder, CO, USA  |4 aut 
773 0 |t Knee Surgery, Sports Traumatology, Arthroscopy  |d Springer Berlin Heidelberg  |g 23/11(2015-11-01), 3383-3392  |x 0942-2056  |q 23:11<3383  |1 2015  |2 23  |o 167 
856 4 0 |u https://doi.org/10.1007/s00167-014-3119-x  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00167-014-3119-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Laver  |D Lior  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Carmont  |D Michael  |u Department of Trauma and Orthopaedic Surgery, Princess Royal Hospital, Telford, Shropshire, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a McConkey  |D Mark  |u Pacific Orthopaedics and Sports Medicine, North Vancouver, BC, Canada  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Palmanovich  |D Ezequiel  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yaacobi  |D Eyal  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Mann  |D Gideon  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nyska  |D Meir  |u Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir” Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kots  |D Eugene  |u Department of Radiology, Sports Medicine Unit, "Meir” Medical Center, Kfar-Saba, Israel  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Mei-Dan  |D Omer  |u Department of Sports Medicine, University of Colorado Hospitals, Boulder, CO, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Knee Surgery, Sports Traumatology, Arthroscopy  |d Springer Berlin Heidelberg  |g 23/11(2015-11-01), 3383-3392  |x 0942-2056  |q 23:11<3383  |1 2015  |2 23  |o 167