Survey of the utility of once-monthly bisphosphonate treatment for improvement of medication adherence in osteoporosis patients in Japan

Verfasser / Beitragende:
[Kazuya Makita, Hiroya Okano, Takefumi Furuya, Tomohiko Urano, Hisashi Hirabayashi, Takami Kumakubo, Jun Iwamoto]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Bone and Mineral Metabolism, 33/1(2015-01-01), 55-60
Format:
Artikel (online)
ID: 605462941
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024 7 0 |a 10.1007/s00774-013-0553-7  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00774-013-0553-7 
245 0 0 |a Survey of the utility of once-monthly bisphosphonate treatment for improvement of medication adherence in osteoporosis patients in Japan  |h [Elektronische Daten]  |c [Kazuya Makita, Hiroya Okano, Takefumi Furuya, Tomohiko Urano, Hisashi Hirabayashi, Takami Kumakubo, Jun Iwamoto] 
520 3 |a Prescription of a bisphosphonate (BP) with monthly dosing has recently been approved in Japan. The value of this approach for improvement of medication adherence was investigated in patients undergoing drug therapy for osteoporosis. A questionnaire was distributed to patients receiving treatment for osteoporosis at 8 medical facilities (5 orthopedic, 2 gynecology, and one internal medicine). Responses were collected from 1,300 patients. After exclusion of those who missed an item on the questionnaire or took drugs other than oral drugs, responses from 1,151 patients were analyzed. The most frequently used drug for treatment of osteoporosis was a once-weekly BP. Of the 1,151 patients, 38.4% reported forgetting to take their current drug. The most frequent concern was ‘I cannot feel an effect', but 73.2% answered ‘I have no concerns'. Regarding the most appropriate dosing regimen for long-term treatment, 60.3% selected once-weekly and 24% selected once every 4weeks. Based on a recommendation by a physician of a drug to be taken monthly, 32.5% wanted to switch, 31.8% were undecided, and 35.7% wanted to continue with their current drug. The desire for a change was higher among patients currently taking a once-weekly BP (52.3%) than among patients taking a daily BP (29.5%) or a SERM (19.4%). This survey revealed patients' preferences in osteoporosis drug therapy. It is important to select a drug for osteoporosis based on the efficacy and the drug regimen preferred by the individual patient. 
540 |a The Japanese Society for Bone and Mineral Research and Springer Japan, 2014 
690 7 |a Osteoporosis  |2 nationallicence 
690 7 |a Bisphosphonate  |2 nationallicence 
690 7 |a Monthly dosing  |2 nationallicence 
690 7 |a Medication adherence  |2 nationallicence 
700 1 |a Makita  |D Kazuya  |u Makita Obstetrics and Gynecology Clinic, 3-3-17 Atago, 352-0021, Niiza, Saitama, Japan  |4 aut 
700 1 |a Okano  |D Hiroya  |u Iidabashi Ladies's Clinic, 102-0072, Tokyo, Japan  |4 aut 
700 1 |a Furuya  |D Takefumi  |u Institute of Rheumatology, Tokyo Women's Medical University, 162-0054, Tokyo, Japan  |4 aut 
700 1 |a Urano  |D Tomohiko  |u Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, 113-0033, Tokyo, Japan  |4 aut 
700 1 |a Hirabayashi  |D Hisashi  |u Department of Orthopedics, Tokyo Adventist Hospital, 167-8507, Tokyo, Japan  |4 aut 
700 1 |a Kumakubo  |D Takami  |u Kumakubo Orthopedics Clinic, 165-0025, Tokyo, Japan  |4 aut 
700 1 |a Iwamoto  |D Jun  |u Institute for Integrated Sports Medicine, School of Medicine, Keio University, 160-8582, Tokyo, Japan  |4 aut 
773 0 |t Journal of Bone and Mineral Metabolism  |d Springer Japan  |g 33/1(2015-01-01), 55-60  |x 0914-8779  |q 33:1<55  |1 2015  |2 33  |o 774 
856 4 0 |u https://doi.org/10.1007/s00774-013-0553-7  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00774-013-0553-7  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Makita  |D Kazuya  |u Makita Obstetrics and Gynecology Clinic, 3-3-17 Atago, 352-0021, Niiza, Saitama, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Okano  |D Hiroya  |u Iidabashi Ladies's Clinic, 102-0072, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Furuya  |D Takefumi  |u Institute of Rheumatology, Tokyo Women's Medical University, 162-0054, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Urano  |D Tomohiko  |u Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, 113-0033, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hirabayashi  |D Hisashi  |u Department of Orthopedics, Tokyo Adventist Hospital, 167-8507, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kumakubo  |D Takami  |u Kumakubo Orthopedics Clinic, 165-0025, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Iwamoto  |D Jun  |u Institute for Integrated Sports Medicine, School of Medicine, Keio University, 160-8582, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Bone and Mineral Metabolism  |d Springer Japan  |g 33/1(2015-01-01), 55-60  |x 0914-8779  |q 33:1<55  |1 2015  |2 33  |o 774