caa a22 4500 605462941 CHVBK 20210128100250.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00774-013-0553-7 doi (NATIONALLICENCE)springer-10.1007/s00774-013-0553-7 Survey of the utility of once-monthly bisphosphonate treatment for improvement of medication adherence in osteoporosis patients in Japan [Elektronische Daten] [Kazuya Makita, Hiroya Okano, Takefumi Furuya, Tomohiko Urano, Hisashi Hirabayashi, Takami Kumakubo, Jun Iwamoto] Prescription of a bisphosphonate (BP) with monthly dosing has recently been approved in Japan. The value of this approach for improvement of medication adherence was investigated in patients undergoing drug therapy for osteoporosis. A questionnaire was distributed to patients receiving treatment for osteoporosis at 8 medical facilities (5 orthopedic, 2 gynecology, and one internal medicine). Responses were collected from 1,300 patients. After exclusion of those who missed an item on the questionnaire or took drugs other than oral drugs, responses from 1,151 patients were analyzed. The most frequently used drug for treatment of osteoporosis was a once-weekly BP. Of the 1,151 patients, 38.4% reported forgetting to take their current drug. The most frequent concern was ‘I cannot feel an effect', but 73.2% answered ‘I have no concerns'. Regarding the most appropriate dosing regimen for long-term treatment, 60.3% selected once-weekly and 24% selected once every 4weeks. Based on a recommendation by a physician of a drug to be taken monthly, 32.5% wanted to switch, 31.8% were undecided, and 35.7% wanted to continue with their current drug. The desire for a change was higher among patients currently taking a once-weekly BP (52.3%) than among patients taking a daily BP (29.5%) or a SERM (19.4%). This survey revealed patients' preferences in osteoporosis drug therapy. It is important to select a drug for osteoporosis based on the efficacy and the drug regimen preferred by the individual patient. The Japanese Society for Bone and Mineral Research and Springer Japan, 2014 Osteoporosis nationallicence Bisphosphonate nationallicence Monthly dosing nationallicence Medication adherence nationallicence Makita Kazuya Makita Obstetrics and Gynecology Clinic, 3-3-17 Atago, 352-0021, Niiza, Saitama, Japan aut Okano Hiroya Iidabashi Ladies's Clinic, 102-0072, Tokyo, Japan aut Furuya Takefumi Institute of Rheumatology, Tokyo Women's Medical University, 162-0054, Tokyo, Japan aut Urano Tomohiko Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, 113-0033, Tokyo, Japan aut Hirabayashi Hisashi Department of Orthopedics, Tokyo Adventist Hospital, 167-8507, Tokyo, Japan aut Kumakubo Takami Kumakubo Orthopedics Clinic, 165-0025, Tokyo, Japan aut Iwamoto Jun Institute for Integrated Sports Medicine, School of Medicine, Keio University, 160-8582, Tokyo, Japan aut Journal of Bone and Mineral Metabolism Springer Japan 33/1(2015-01-01), 55-60 0914-8779 33:1<55 2015 33 774 https://doi.org/10.1007/s00774-013-0553-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00774-013-0553-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Makita Kazuya Makita Obstetrics and Gynecology Clinic, 3-3-17 Atago, 352-0021, Niiza, Saitama, Japan aut NATIONALLICENCE 700 1- Okano Hiroya Iidabashi Ladies's Clinic, 102-0072, Tokyo, Japan aut NATIONALLICENCE 700 1- Furuya Takefumi Institute of Rheumatology, Tokyo Women's Medical University, 162-0054, Tokyo, Japan aut NATIONALLICENCE 700 1- Urano Tomohiko Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, 113-0033, Tokyo, Japan aut NATIONALLICENCE 700 1- Hirabayashi Hisashi Department of Orthopedics, Tokyo Adventist Hospital, 167-8507, Tokyo, Japan aut NATIONALLICENCE 700 1- Kumakubo Takami Kumakubo Orthopedics Clinic, 165-0025, Tokyo, Japan aut NATIONALLICENCE 700 1- Iwamoto Jun Institute for Integrated Sports Medicine, School of Medicine, Keio University, 160-8582, Tokyo, Japan aut NATIONALLICENCE 773 0- Journal of Bone and Mineral Metabolism Springer Japan 33/1(2015-01-01), 55-60 0914-8779 33:1<55 2015 33 774