The FRAX® as a predictor of mortality in Japanese incident hemodialysis patients: an observational, follow-up study
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| 024 | 7 | 0 | |a 10.1007/s00774-014-0631-5 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00774-014-0631-5 | ||
| 245 | 0 | 4 | |a The FRAX® as a predictor of mortality in Japanese incident hemodialysis patients: an observational, follow-up study |h [Elektronische Daten] |c [Toshihide Hayashi, Nobuhiko Joki, Yuri Tanaka, Masaki Iwasaki, Shun Kubo, Takasuke Asakawa, Ai Matsukane, Yasunori Takahashi, Yoshihiko Imamura, Koichi Hirahata, Hiroki Hase] |
| 520 | 3 | |a The World Health Organization Fracture Risk Assessment Tool (FRAX®) was recently developed to estimate the 10-year absolute risk of osteoporotic fracture among the general population. However, the evidence for its use in chronic kidney disease patients has been lacking, and the association between the FRAX® and mortality is unknown. Therefore, a hospital-based, prospective, cohort study was conducted to evaluate the predictive ability of the FRAX® for mortality in hemodialysis patients. A total of 252 patients who had been started on maintenance hemodialysis, 171 men and 81 women, with a mean age of 67±14years, was studied. The endpoint was defined as all-cause death. The Cox proportional hazards model was used to calculate hazard ratios and 95% confidence intervals. During the mean follow-up period of 3.4±2.7years, 61 deaths occurred. The median (interquartile range) of the FRAX® for major osteoporotic fracture was 6.9 (4.6-12.0) % in men and 19.0 (7.6-33.0) % in women. Cumulative survival rates at 5years after starting dialysis, with the FRAX® levels above and below the median, were 51.9 and 87.9%, respectively, in men and 67.4 and 83.7%, respectively, in women. Overall, in men, the multivariate Cox regression analyses revealed that the log-transformed FRAX® remained an independent predictor of death after adjusting by confounding variables. However, in women, the significant association between the FRAX® value and the outcome was eliminated if age was put into these models. Among Japanese hemodialysis patients, the FRAX® seems to be useful for predicting death, especially in men. | |
| 540 | |a The Japanese Society for Bone and Mineral Research and Springer Japan, 2015 | ||
| 690 | 7 | |a CKD |2 nationallicence | |
| 690 | 7 | |a FRAX |2 nationallicence | |
| 690 | 7 | |a Hemodialysis |2 nationallicence | |
| 690 | 7 | |a Mortality |2 nationallicence | |
| 700 | 1 | |a Hayashi |D Toshihide |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Joki |D Nobuhiko |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Tanaka |D Yuri |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Iwasaki |D Masaki |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Kubo |D Shun |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Asakawa |D Takasuke |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Matsukane |D Ai |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Takahashi |D Yasunori |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Imamura |D Yoshihiko |u Division of Dialysis, Nissan Tamagawa Hospital, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Hirahata |D Koichi |u Hirahata Clinic, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Hase |D Hiroki |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | |
| 773 | 0 | |t Journal of Bone and Mineral Metabolism |d Springer Japan |g 33/6(2015-11-01), 674-683 |x 0914-8779 |q 33:6<674 |1 2015 |2 33 |o 774 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00774-014-0631-5 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00774-014-0631-5 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Hayashi |D Toshihide |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Joki |D Nobuhiko |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tanaka |D Yuri |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Iwasaki |D Masaki |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kubo |D Shun |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Asakawa |D Takasuke |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Matsukane |D Ai |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Takahashi |D Yasunori |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Imamura |D Yoshihiko |u Division of Dialysis, Nissan Tamagawa Hospital, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Hirahata |D Koichi |u Hirahata Clinic, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Hase |D Hiroki |u Division of Nephrology, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-Ku, 153-8515, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Bone and Mineral Metabolism |d Springer Japan |g 33/6(2015-11-01), 674-683 |x 0914-8779 |q 33:6<674 |1 2015 |2 33 |o 774 | ||