Chronic kidney disease and bone metabolism
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| 024 | 7 | 0 | |a 10.1007/s00774-014-0639-x |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00774-014-0639-x | ||
| 245 | 0 | 0 | |a Chronic kidney disease and bone metabolism |h [Elektronische Daten] |c [Junichiro Kazama, Koji Matsuo, Yoshiko Iwasaki, Masafumi Fukagawa] |
| 520 | 3 | |a Chronic kidney disease-related mineral and bone disease (CKD-MBD) is a syndrome defined as a systemic mineral metabolic disorder associated with CKD, and the term renal osteodystrophy indicates a pathomorphological concept of bone lesions associated with CKD-MBD. Cortical bone thinning, abnormalities in bone turnover and primary/secondary mineralization, elevated levels of circulating sclerostin, increased apoptosis in osteoblasts and osteocytes, disturbance of the coupling phenomenon, iatrogenic factors, accumulated micro-crackles, crystal/collagen disorientation, and chemical modification of collagen crosslinks are all possible candidates found in CKD that could promote osteopenia and/or bone fragility. Some of above factors are the consequences of abnormal systemic mineral metabolism but for others it seem unlikely. We have used the term uremic osteoporosis to describe the uremia-induced bone fragility which is not derived from abnormal systemic mineral metabolism. Interestingly, the disease aspect of uremic osteoporosis appears to be similar to that of senile osteoporosis. | |
| 540 | |a The Japanese Society for Bone and Mineral Research and Springer Japan, 2015 | ||
| 690 | 7 | |a Chronic kidney disease (CKD) |2 nationallicence | |
| 690 | 7 | |a Chronic kidney disease-related mineral and bone disease (CKD-MBD) |2 nationallicence | |
| 690 | 7 | |a Uremic osteoporosis |2 nationallicence | |
| 690 | 7 | |a Material property |2 nationallicence | |
| 700 | 1 | |a Kazama |D Junichiro |u Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan |4 aut | |
| 700 | 1 | |a Matsuo |D Koji |u Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan |4 aut | |
| 700 | 1 | |a Iwasaki |D Yoshiko |u Department of Health Sciences, Oita University of Nursing and Health Sciences, Oita, Japan |4 aut | |
| 700 | 1 | |a Fukagawa |D Masafumi |u Division of Nephrology and Metabolism, Tokai University School of Medicine, Isehara, Japan |4 aut | |
| 773 | 0 | |t Journal of Bone and Mineral Metabolism |d Springer Japan |g 33/3(2015-05-01), 245-252 |x 0914-8779 |q 33:3<245 |1 2015 |2 33 |o 774 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00774-014-0639-x |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a review-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00774-014-0639-x |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kazama |D Junichiro |u Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Matsuo |D Koji |u Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Iwasaki |D Yoshiko |u Department of Health Sciences, Oita University of Nursing and Health Sciences, Oita, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fukagawa |D Masafumi |u Division of Nephrology and Metabolism, Tokai University School of Medicine, Isehara, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Bone and Mineral Metabolism |d Springer Japan |g 33/3(2015-05-01), 245-252 |x 0914-8779 |q 33:3<245 |1 2015 |2 33 |o 774 | ||