caa a22 4500 605463158 CHVBK 20210128100252.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1007/s00774-014-0606-6 doi (NATIONALLICENCE)springer-10.1007/s00774-014-0606-6 Atypical femoral fracture in a patient treated with denosumab [Elektronische Daten] [Kareeann Khow, Tuck Yong] Atypical fractures of the femur (AFF) have been reported in the literature at an increasing rate over the past decade, especially in patients who have been on prolonged courses of bisphosphonates. However, there have only been a few reported cases of AFF in those treated with other antiresorptive medications. In this case report, a 72-year-old woman with chronic obstructive pulmonary disease and osteoporosis presented with an atraumatic right femoral fracture in the setting of denosumab use. In contrast with other reports, this patient had received bisphosphonate therapy for a short duration before the switch to denosumab. While causality between the fracture and denosumab use cannot be established in this case, there is a growing number of reports of a similar association. Ongoing vigilance is required to determine whether denosumab is associated with or potentially a cause of AFF. The Japanese Society for Bone and Mineral Research and Springer Japan, 2014 Atypical femoral fractures nationallicence Denosumab nationallicence Osteoporosis nationallicence Khow Kareeann Department of Aged and Extended Care, The Queen Elizabeth Hospital and University of Adelaide, Adelaide, SA, Australia aut Yong Tuck Flinders Private Hospital, Flinders Drive, Bedford Park, 5042, Adelaide, SA, Australia aut Journal of Bone and Mineral Metabolism Springer Japan 33/3(2015-05-01), 355-358 0914-8779 33:3<355 2015 33 774 https://doi.org/10.1007/s00774-014-0606-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00774-014-0606-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Khow Kareeann Department of Aged and Extended Care, The Queen Elizabeth Hospital and University of Adelaide, Adelaide, SA, Australia aut NATIONALLICENCE 700 1- Yong Tuck Flinders Private Hospital, Flinders Drive, Bedford Park, 5042, Adelaide, SA, Australia aut NATIONALLICENCE 773 0- Journal of Bone and Mineral Metabolism Springer Japan 33/3(2015-05-01), 355-358 0914-8779 33:3<355 2015 33 774