The incidence of and risk factors for developing atypical femoral fractures in Japan
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| 024 | 7 | 0 | |a 10.1007/s00774-014-0591-9 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00774-014-0591-9 | ||
| 245 | 0 | 4 | |a The incidence of and risk factors for developing atypical femoral fractures in Japan |h [Elektronische Daten] |c [Yoshitomo Saita, Muneaki Ishijima, Atsuhiko Mogami, Mitsuaki Kubota, Tomonori Baba, Takefumi Kaketa, Masashi Nagao, Yuko Sakamoto, Kensuke Sakai, Yasuhiro Homma, Rui Kato, Nana Nagura, Kei Miyagawa, Tomoki Wada, Lizu Liu, Joe Matsuoka, Osamu Obayashi, Katsuo Shitoto, Masahiko Nozawa, Hajime Kajihara, Hogaku Gen, Kazuo Kaneko] |
| 520 | 3 | |a The long-term treatment with anti-resorptive drugs for osteoporotic patients is suggested to be associated with an increase in atypical femoral fractures (AFFs). However, their incidence, patient characteristics, and risk factors have not been fully elucidated especially in Asian countries. This retrospective observational cohort study found fourteen AFFs in ten patients (four bilateral fractures) among 2,238 hip and femoral shaft fractures treated in our associated hospitals between 2005 and 2010; this incidence (0.63%) was similar to Caucasians. Of the ten patients with AFFs, nine (90%) and six (60%) were using bisphosphonates (BPs) and glucocorticoids (GCs), respectively, compared to 14.3 and 8.6% for patients with typical femoral fractures who were using these agents. As comorbid conditions, five patients had collagen disease (CD) and two had diabetes. A fracture location-, age- and gender-matched (1:3) case-control study revealed that administration of BPs, GCs, and suffering from collagen disease (CD) were significant risk factors for developing AFFs [odds ratios 36.0 (95% confidence intervals 3.8-342.2), 13.0 (2.3-74.1) and 9.0 (1.6-50.3), respectively]. Interestingly, all of the patients with atypical subtrochanteric femoral fractures, defined as those within 5cm of the lesser trochanter, were taking GCs due to CD, and the age of these patients (average of 54.8years) was significantly younger than those with atypical diaphyseal femoral fractures (average of 77.2years, p<0.05). In conclusion, the incidence of AFFs in the Japanese population was similar to that of Caucasians, and taking BPs and GCs and suffering from CD were risk factors for developing AFFs. | |
| 540 | |a The Japanese Society for Bone and Mineral Research and Springer Japan, 2014 | ||
| 690 | 7 | |a Atypical femoral fracture (AFF) |2 nationallicence | |
| 690 | 7 | |a Osteoporosis |2 nationallicence | |
| 690 | 7 | |a Bisphosphonate |2 nationallicence | |
| 690 | 7 | |a Glucocorticoid |2 nationallicence | |
| 690 | 7 | |a Collagen disease |2 nationallicence | |
| 700 | 1 | |a Saita |D Yoshitomo |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Ishijima |D Muneaki |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Mogami |D Atsuhiko |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | |
| 700 | 1 | |a Kubota |D Mitsuaki |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Baba |D Tomonori |u Department of Orthopaedic Surgery, Juntendo Urayasu Hospital, Chiba, Japan |4 aut | |
| 700 | 1 | |a Kaketa |D Takefumi |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Nagao |D Masashi |u Department of Orthopaedic Surgery, Juntendo Nerima Hospital, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Sakamoto |D Yuko |u Department of Orthopaedic Surgery, Juntendo Nerima Hospital, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Sakai |D Kensuke |u Department of Orthopaedic Surgery, Juntendo Nerima Hospital, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Homma |D Yasuhiro |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | |
| 700 | 1 | |a Kato |D Rui |u Department of Orthopaedic Surgery, Koto Hospital, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Nagura |D Nana |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | |
| 700 | 1 | |a Miyagawa |D Kei |u Department of Orthopaedic Surgery, Chiba Central Medical Center, Chiba, Japan |4 aut | |
| 700 | 1 | |a Wada |D Tomoki |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | |
| 700 | 1 | |a Liu |D Lizu |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Matsuoka |D Joe |u Juntendo Clinical Research Center, Juntendo University, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Obayashi |D Osamu |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | |
| 700 | 1 | |a Shitoto |D Katsuo |u Department of Orthopaedic Surgery, Juntendo Urayasu Hospital, Chiba, Japan |4 aut | |
| 700 | 1 | |a Nozawa |D Masahiko |u Department of Orthopaedic Surgery, Juntendo Nerima Hospital, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Kajihara |D Hajime |u Department of Orthopaedic Surgery, Koto Hospital, Tokyo, Japan |4 aut | |
| 700 | 1 | |a Gen |D Hogaku |u Department of Orthopaedic Surgery, Chiba Central Medical Center, Chiba, Japan |4 aut | |
| 700 | 1 | |a Kaneko |D Kazuo |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | |
| 773 | 0 | |t Journal of Bone and Mineral Metabolism |d Springer Japan |g 33/3(2015-05-01), 311-318 |x 0914-8779 |q 33:3<311 |1 2015 |2 33 |o 774 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00774-014-0591-9 |q text/html |z Onlinezugriff via DOI |
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00774-014-0591-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Saita |D Yoshitomo |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ishijima |D Muneaki |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mogami |D Atsuhiko |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kubota |D Mitsuaki |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Baba |D Tomonori |u Department of Orthopaedic Surgery, Juntendo Urayasu Hospital, Chiba, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kaketa |D Takefumi |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nagao |D Masashi |u Department of Orthopaedic Surgery, Juntendo Nerima Hospital, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sakamoto |D Yuko |u Department of Orthopaedic Surgery, Juntendo Nerima Hospital, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sakai |D Kensuke |u Department of Orthopaedic Surgery, Juntendo Nerima Hospital, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Homma |D Yasuhiro |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kato |D Rui |u Department of Orthopaedic Surgery, Koto Hospital, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nagura |D Nana |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Miyagawa |D Kei |u Department of Orthopaedic Surgery, Chiba Central Medical Center, Chiba, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wada |D Tomoki |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Liu |D Lizu |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Matsuoka |D Joe |u Juntendo Clinical Research Center, Juntendo University, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Obayashi |D Osamu |u Department of Orthopaedic Surgery, Juntendo Shizuoka Hospital, Shizuoka, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shitoto |D Katsuo |u Department of Orthopaedic Surgery, Juntendo Urayasu Hospital, Chiba, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nozawa |D Masahiko |u Department of Orthopaedic Surgery, Juntendo Nerima Hospital, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kajihara |D Hajime |u Department of Orthopaedic Surgery, Koto Hospital, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gen |D Hogaku |u Department of Orthopaedic Surgery, Chiba Central Medical Center, Chiba, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kaneko |D Kazuo |u Department of Orthopaedics, Juntendo University Faculty of Medicine, Tokyo, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Bone and Mineral Metabolism |d Springer Japan |g 33/3(2015-05-01), 311-318 |x 0914-8779 |q 33:3<311 |1 2015 |2 33 |o 774 | ||