Incidence of disability and its associated factors in Japanese men and women: the Longitudinal Cohorts of Motor System Organ (LOCOMO) study

Verfasser / Beitragende:
[Noriko Yoshimura, Toru Akune, Saeko Fujiwara, Yoko Shimizu, Hideyo Yoshida, Yuji Nishiwaki, Akihiro Sudo, Go Omori, Munehito Yoshida, Hiroshi Shimokata, Takao Suzuki, Shigeyuki Muraki, Hiroyuki Oka, Kozo Nakamura]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Bone and Mineral Metabolism, 33/2(2015-03-01), 186-191
Format:
Artikel (online)
ID: 605463549
LEADER caa a22 4500
001 605463549
003 CHVBK
005 20210128100254.0
007 cr unu---uuuuu
008 210128e20150301xx s 000 0 eng
024 7 0 |a 10.1007/s00774-014-0573-y  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00774-014-0573-y 
245 0 0 |a Incidence of disability and its associated factors in Japanese men and women: the Longitudinal Cohorts of Motor System Organ (LOCOMO) study  |h [Elektronische Daten]  |c [Noriko Yoshimura, Toru Akune, Saeko Fujiwara, Yoko Shimizu, Hideyo Yoshida, Yuji Nishiwaki, Akihiro Sudo, Go Omori, Munehito Yoshida, Hiroshi Shimokata, Takao Suzuki, Shigeyuki Muraki, Hiroyuki Oka, Kozo Nakamura] 
520 3 |a We investigated the incidence of disability and its risk factors in older Japanese adults to establish an evidence-based disability prevention strategy for this population. For this purpose, we used data from the Longitudinal Cohorts of Motor System Organ (LOCOMO) study, initiated in 2008 to integrate information from cohorts in nine communities across Japan: Tokyo (two regions), Wakayama (two regions), Hiroshima, Niigata, Mie, Akita, and Gunma prefectures. We examined the annual occurrence of disability from 8,454 individuals (2,705 men and 5,749 women) aged ≥65years. The estimated incidence of disability was 3.58/100 person-years (p-y) (men: 3.17/100 p-y; women: 3.78/100 p-y). To determine factors associated with disability, Cox's proportional hazard model was used, with the occurrence of disability as an objective variable and age (+1year), gender (vs. women), body build (0: normal/overweight range, BMI 18.5-27.5kg/m2; 1: emaciation, BMI <18.5kg/m2; 2: obesity, BMI >27.5kg/m2), and regional differences (0: rural areas including Wakayama, Niigata, Mie, Akita, and Gunma vs. 1: urban areas including Tokyo and Hiroshima) as explanatory variables. Age, body build, and regional difference significantly influenced the occurrence of disability (age, +1year: hazard ratio 1.13, 95% confidence interval 1.12-1.15, p<0.001; body build, vs. emaciation: 1.24, 1.01-1.53, p=0.041; body build, vs. obesity: 1.36, 1.08-1.71, p=0.009; residence, vs. living in rural areas: 1.59, 1.37-1.85, p<0.001). We concluded that higher age, both emaciation and obesity, and living in rural areas would be risk factors for the occurrence of disability. 
540 |a The Japanese Society for Bone and Mineral Research and Springer Japan, 2014 
690 7 |a Nation-wide population-based cohort study  |2 nationallicence 
690 7 |a Epidemiology  |2 nationallicence 
690 7 |a Incidence  |2 nationallicence 
690 7 |a Disability  |2 nationallicence 
690 7 |a Body build  |2 nationallicence 
700 1 |a Yoshimura  |D Noriko  |u Department of Joint Disease Research, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan  |4 aut 
700 1 |a Akune  |D Toru  |u Department of Clinical Motor System Medicine, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, Tokyo, Japan  |4 aut 
700 1 |a Fujiwara  |D Saeko  |u Hiroshima Atomic Bomb Causality Council, Hiroshima, Japan  |4 aut 
700 1 |a Shimizu  |D Yoko  |u Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan  |4 aut 
700 1 |a Yoshida  |D Hideyo  |u Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan  |4 aut 
700 1 |a Nishiwaki  |D Yuji  |u Department of Environmental and Occupational Health, School of Medicine, Toho University, Tokyo, Japan  |4 aut 
700 1 |a Sudo  |D Akihiro  |u Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Mie, Japan  |4 aut 
700 1 |a Omori  |D Go  |u Center for Transdisciplinary Research, Institute for Research Promotion, Niigata University, Niigata, Japan  |4 aut 
700 1 |a Yoshida  |D Munehito  |u Department of Orthopedic Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan  |4 aut 
700 1 |a Shimokata  |D Hiroshi  |u Graduate School of Nutritional Sciences, Nagoya University of Arts and Sciences, Aichi, Japan  |4 aut 
700 1 |a Suzuki  |D Takao  |u National Center for Geriatrics and Gerontology, Aichi, Japan  |4 aut 
700 1 |a Muraki  |D Shigeyuki  |u Department of Clinical Motor System Medicine, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, Tokyo, Japan  |4 aut 
700 1 |a Oka  |D Hiroyuki  |u Department of Joint Disease Research, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan  |4 aut 
700 1 |a Nakamura  |D Kozo  |u National Rehabilitation Center for Persons with Disabilities, Saitama, Japan  |4 aut 
773 0 |t Journal of Bone and Mineral Metabolism  |d Springer Japan  |g 33/2(2015-03-01), 186-191  |x 0914-8779  |q 33:2<186  |1 2015  |2 33  |o 774 
856 4 0 |u https://doi.org/10.1007/s00774-014-0573-y  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00774-014-0573-y  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yoshimura  |D Noriko  |u Department of Joint Disease Research, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Akune  |D Toru  |u Department of Clinical Motor System Medicine, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fujiwara  |D Saeko  |u Hiroshima Atomic Bomb Causality Council, Hiroshima, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shimizu  |D Yoko  |u Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yoshida  |D Hideyo  |u Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nishiwaki  |D Yuji  |u Department of Environmental and Occupational Health, School of Medicine, Toho University, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sudo  |D Akihiro  |u Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Mie, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Omori  |D Go  |u Center for Transdisciplinary Research, Institute for Research Promotion, Niigata University, Niigata, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yoshida  |D Munehito  |u Department of Orthopedic Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shimokata  |D Hiroshi  |u Graduate School of Nutritional Sciences, Nagoya University of Arts and Sciences, Aichi, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Suzuki  |D Takao  |u National Center for Geriatrics and Gerontology, Aichi, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Muraki  |D Shigeyuki  |u Department of Clinical Motor System Medicine, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Oka  |D Hiroyuki  |u Department of Joint Disease Research, 22nd Century Medical and Research Center, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nakamura  |D Kozo  |u National Rehabilitation Center for Persons with Disabilities, Saitama, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Bone and Mineral Metabolism  |d Springer Japan  |g 33/2(2015-03-01), 186-191  |x 0914-8779  |q 33:2<186  |1 2015  |2 33  |o 774