caa a22 4500 605464200 CHVBK 20210128100257.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10499-014-9800-8 doi (NATIONALLICENCE)springer-10.1007/s10499-014-9800-8 Quantitative change of red seabream iridovirus (RSIV) in rock bream Oplegnathus fasciatus , following Poly(I:C) administration [Elektronische Daten] [So-Young Oh, Wi-Sik Kim, Myung-Joo Oh, Toyohiko Nishizawa] Serious economic losses due to red seabream iridovirus (RSIV) infection have occurred in fingerlings and market-sized rock bream Oplegnathus fasciatus in Korea. Previously, it was demonstrated that fishes immunized with a live fish RNA virus following polyinosinic-polycytidylic acid [Poly(I:C), an inducer of interferon (IFN)] administrationwere protected from the viral infection [Poly(I:C) immunization with live virus]; however, rock bream administered Poly(I:C) were not protected from RSIV infection, although IFN was expressed well in rock bream that received Poly(I:C). In this study, we investigated kinetics of the RSIV in rock bream that did or did not receive Poly(I:C). No significant difference was observed in the mortality pattern due to RSIV infection regardless of Poly(I:C) administration, indicating that rock bream administered Poly(I:C) were not protected from RSIV infection. No significant difference was observed in the pattern of RSIV kinetics between the fishes that did or did not receive Poly(I:C). We would conclude that RSIV is resistant to IFN induction in rock bream. Springer International Publishing Switzerland, 2014 Red seabream iridovirus nationallicence Megalocytivirus nationallicence Interferon nationallicence Poly(I:C) nationallicence RSIV nationallicence Innate immune response nationallicence Kinetics nationallicence RSIV : Red seabream iridovirus nationallicence Poly(I:C) : Polyinosinic-polycytidylic acid nationallicence IFN : Interferon nationallicence NNV : Nervous necrosis virus nationallicence qPCR : Quantitative polymerase chain reaction nationallicence DEPC : Diethylpyrocarbonate nationallicence Oh So-Young Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, 550-749, Yeosu, Republic of Korea aut Kim Wi-Sik Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, 550-749, Yeosu, Republic of Korea aut Oh Myung-Joo Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, 550-749, Yeosu, Republic of Korea aut Nishizawa Toyohiko Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, 550-749, Yeosu, Republic of Korea aut Aquaculture International Springer International Publishing 23/1(2015-02-01), 93-98 0967-6120 23:1<93 2015 23 10499 https://doi.org/10.1007/s10499-014-9800-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10499-014-9800-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Oh So-Young Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, 550-749, Yeosu, Republic of Korea aut NATIONALLICENCE 700 1- Kim Wi-Sik Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, 550-749, Yeosu, Republic of Korea aut NATIONALLICENCE 700 1- Oh Myung-Joo Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, 550-749, Yeosu, Republic of Korea aut NATIONALLICENCE 700 1- Nishizawa Toyohiko Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University, 550-749, Yeosu, Republic of Korea aut NATIONALLICENCE 773 0- Aquaculture International Springer International Publishing 23/1(2015-02-01), 93-98 0967-6120 23:1<93 2015 23 10499