caa a22 4500 605464936 CHVBK 20210128100300.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10499-014-9844-9 doi (NATIONALLICENCE)springer-10.1007/s10499-014-9844-9 Polysaccharide from Enteromorpha prolifera enhances non-specific immune responses and protection against Vibrio splendidus infection of sea cucumber [Elektronische Daten] [Jianteng Wei, Shuxian Wang, Dong Pei, Yongfeng Liu, Yi Liu, Duolong Di] This study aimed to evaluate the effects of polysaccharide from Enteromorpha prolifera (PEP2) on the non-specific immune responses of sea cucumber. The non-specific humoral and cellular responses were determined, and sea cucumbers were challenged by Vibrio splendidus. The results indicate that PEP2 had no significant effect on the total coelomocyte counts. Both phagocytic capacity and respiratory burst activity were significantly increased by PEP2. Among the humoral responses, the activities of acid phosphatase, catalase and superoxide dismutase of sea cucumber were significantly enhanced by PEP2. However, no difference in alkaline phosphatase activity was observed between the experimental and control groups. In the challenge test, we found that PEP2 decreased the mortality rate of sea cucumbers and enhanced their resistance to V. splendidus. Thus, PEP2 could enhance the non-specific immune activity of sea cucumbers. PEP2 exhibited potent immunomodulatory properties and can be explored as a novel potential immunostimulant of sea cucumber. Springer International Publishing Switzerland, 2014 Enteromorpha prolifera nationallicence Non-specific immune response nationallicence Polysaccharide nationallicence Protection nationallicence Sea cucumber nationallicence Wei Jianteng Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut Wang Shuxian Mariculture Institute of Shandong Province, 266002, Qingdao, People's Republic of China aut Pei Dong Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut Liu Yongfeng Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut Liu Yi Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut Di Duolong Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut Aquaculture International Springer International Publishing 23/2(2015-04-01), 661-670 0967-6120 23:2<661 2015 23 10499 https://doi.org/10.1007/s10499-014-9844-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10499-014-9844-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wei Jianteng Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut NATIONALLICENCE 700 1- Wang Shuxian Mariculture Institute of Shandong Province, 266002, Qingdao, People's Republic of China aut NATIONALLICENCE 700 1- Pei Dong Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut NATIONALLICENCE 700 1- Liu Yongfeng Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut NATIONALLICENCE 700 1- Liu Yi Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut NATIONALLICENCE 700 1- Di Duolong Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 18 Tianshui Middle Road, 730000, Lanzhou, People's Republic of China aut NATIONALLICENCE 773 0- Aquaculture International Springer International Publishing 23/2(2015-04-01), 661-670 0967-6120 23:2<661 2015 23 10499