A computational extensional rheology study of two biofluid systems

Verfasser / Beitragende:
[Jose López-Aguilar, Michael Webster, Alaa Al-Muslimawi, Hamid Tamaddon-Jahromi, Rhodri Williams, Karl Hawkins, Colin Askill, Chin Ch'ng, Gwyneth Davies, Phillip Ebden, Keir Lewis]
Ort, Verlag, Jahr:
2015
Enthalten in:
Rheologica Acta, 54/4(2015-04-01), 287-305
Format:
Artikel (online)
ID: 60546653X
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024 7 0 |a 10.1007/s00397-014-0830-y  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00397-014-0830-y 
245 0 2 |a A computational extensional rheology study of two biofluid systems  |h [Elektronische Daten]  |c [Jose López-Aguilar, Michael Webster, Alaa Al-Muslimawi, Hamid Tamaddon-Jahromi, Rhodri Williams, Karl Hawkins, Colin Askill, Chin Ch'ng, Gwyneth Davies, Phillip Ebden, Keir Lewis] 
520 3 |a The main focus of the present computational modelling work is to determine the extensional rheological response of some model biofluids, with a view to ultimately aiding experimentally based analyses and clinical practice. This is accomplished in the present study through model extensional flows and rheological investigation, addressing filament stretching and contraction flows, and upon which significant advances are presented. As such, two biofluid flow systems within the human body are of current interest: (i) respiratory disorders and sputum in the lung airways (associated with filament stretching), where stretchiness of mucus sputum in situ is vital, with clinical focus on chronic obstructive pulmonary disease (COPD/sputum); and (ii) bile flow in the biliary system (contraction flow), with clinical focus on disorders of primary sclerosis cholangitis and common bile duct narrowing. Both sputum and bile biofluid systems are represented through kinetic theory rheological fluid modelling, with capability to represent material structure entanglement, branching and anisotropy. This is practically achieved by appealing to the class of pom-pom differential constitutive models, extracted from polymer melt physics and deployed here through a single extended pom-pom (SXPP) approximation. This class of models is sufficiently rich to enable description of both network structure and rheological properties, exhibiting viscoelastic response (memory), with strain-hardening/softening and shear-thinning properties. 
540 |a Springer-Verlag Berlin Heidelberg, 2014 
690 7 |a CFD biorheology  |2 nationallicence 
690 7 |a Contraction flows  |2 nationallicence 
690 7 |a Bile duct disorders  |2 nationallicence 
690 7 |a Filament stretching  |2 nationallicence 
690 7 |a Respiratory disorders COPD  |2 nationallicence 
690 7 |a Sputum  |2 nationallicence 
700 1 |a López-Aguilar  |D Jose  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Webster  |D Michael  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Al-Muslimawi  |D Alaa  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Tamaddon-Jahromi  |D Hamid  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Williams  |D Rhodri  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Hawkins  |D Karl  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Askill  |D Colin  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Ch'ng  |D Chin  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Davies  |D Gwyneth  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Ebden  |D Phillip  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
700 1 |a Lewis  |D Keir  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
773 0 |t Rheologica Acta  |d Springer Berlin Heidelberg  |g 54/4(2015-04-01), 287-305  |x 0035-4511  |q 54:4<287  |1 2015  |2 54  |o 397 
856 4 0 |u https://doi.org/10.1007/s00397-014-0830-y  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00397-014-0830-y  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a López-Aguilar  |D Jose  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Webster  |D Michael  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Al-Muslimawi  |D Alaa  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tamaddon-Jahromi  |D Hamid  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Williams  |D Rhodri  |u INNFM, College of Engineering, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hawkins  |D Karl  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Askill  |D Colin  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ch'ng  |D Chin  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Davies  |D Gwyneth  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ebden  |D Phillip  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lewis  |D Keir  |u College of Medicine, Swansea University, SA28PP, Swansea, UK  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Rheologica Acta  |d Springer Berlin Heidelberg  |g 54/4(2015-04-01), 287-305  |x 0035-4511  |q 54:4<287  |1 2015  |2 54  |o 397