Adjustment of basal insulin infusion rate in T1DM by hybrid PSO

Verfasser / Beitragende:
[Zhijiang Lou, Bo Liu, Hongzhi Xie, Youqing Wang]
Ort, Verlag, Jahr:
2015
Enthalten in:
Soft Computing, 19/7(2015-07-01), 1921-1937
Format:
Artikel (online)
ID: 605469059
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024 7 0 |a 10.1007/s00500-014-1378-6  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00500-014-1378-6 
245 0 0 |a Adjustment of basal insulin infusion rate in T1DM by hybrid PSO  |h [Elektronische Daten]  |c [Zhijiang Lou, Bo Liu, Hongzhi Xie, Youqing Wang] 
520 3 |a Basal insulin infusion rate which should be adjusted to increase or decrease insulin delivery with the varying blood sugar level plays a key role in type 1 diabetes mellitus (T1DM) patients for maintaining the blood glucose level approximately steady within reference range in order to avoid the complications developed from diabetes. This paper proposes an effective hybrid particle swarm optimization (HPSO) algorithm for solving the basal insulin infusion rate problem. In HPSO, bad experience lesson learning scheme and local search based on chaotic dynamics are proposed to make a good balance between global exploration and local exploitation. Simulation results based on a set of well-known optimization benchmark instances and the basal insulin infusion rate adjustment problem for T1DM demonstrate the effectiveness of the proposed HPSO. In silico tests on standard virtual subject via HPSO show that under nominal condition the blood glucose concentrations could be kept within a range of 80-150mg/dL within less than 5days; meanwhile, in case of random variations in meal timings within $$\pm $$ ± 60min or meal amounts within $$\pm $$ ± 75% deviation from the nominal values, the blood glucose concentrations could be kept within the safe regions. 
540 |a Springer-Verlag Berlin Heidelberg, 2014 
690 7 |a Particle swarm optimization (PSO)  |2 nationallicence 
690 7 |a Glycemic control  |2 nationallicence 
690 7 |a Basal insulin infusion rate optimization  |2 nationallicence 
690 7 |a Type 1 diabetes mellitus  |2 nationallicence 
700 1 |a Lou  |D Zhijiang  |u College of Information Science and Technology, Beijing University of Chemical Technology, Beijing, China  |4 aut 
700 1 |a Liu  |D Bo  |u Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, China  |4 aut 
700 1 |a Xie  |D Hongzhi  |u College of Information Science and Technology, Beijing University of Chemical Technology, Beijing, China  |4 aut 
700 1 |a Wang  |D Youqing  |u College of Information Science and Technology, Beijing University of Chemical Technology, Beijing, China  |4 aut 
773 0 |t Soft Computing  |d Springer Berlin Heidelberg  |g 19/7(2015-07-01), 1921-1937  |x 1432-7643  |q 19:7<1921  |1 2015  |2 19  |o 500 
856 4 0 |u https://doi.org/10.1007/s00500-014-1378-6  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00500-014-1378-6  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lou  |D Zhijiang  |u College of Information Science and Technology, Beijing University of Chemical Technology, Beijing, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Liu  |D Bo  |u Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Xie  |D Hongzhi  |u College of Information Science and Technology, Beijing University of Chemical Technology, Beijing, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wang  |D Youqing  |u College of Information Science and Technology, Beijing University of Chemical Technology, Beijing, China  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Soft Computing  |d Springer Berlin Heidelberg  |g 19/7(2015-07-01), 1921-1937  |x 1432-7643  |q 19:7<1921  |1 2015  |2 19  |o 500