caa a22 4500 605475105 CHVBK 20210128100350.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s10516-014-9243-x doi (NATIONALLICENCE)springer-10.1007/s10516-014-9243-x van Eck Dingmar Ghent University, Centre for Logic and Philosophy of Science, Ghent, Belgium aut Reconciling Ontic and Epistemic Constraints on Mechanistic Explanation, Epistemically [Elektronische Daten] [Dingmar van Eck] In this paper I address the current debate on ontic versus epistemic conceptualizations of mechanistic explanation in the mechanisms literature. Illari recently argued that good explanations are subject to both ontic and epistemic constraints: they must describe mechanisms in the world (ontic aim) in such fashion that they provide understanding of their workings (epistemic aim). Elaborating upon Illari's ‘integration' account, I argue that causal role function discovery of mechanisms and their components is an epistemic prerequisite for achieving these two aims. This analysis extends Illari's account in important ways, putting more pressure on ontic readings of mechanistic explanation and providing an answer to the question how ontic and epistemic constraints on mechanistic explanation are related. I argue these point in terms of cases on memory research drawn from neuroscience and research on extinct neurogenetic mechanisms from early nervous systems biology. Springer Science+Business Media Dordrecht, 2014 Mechanistic explanation nationallicence Ontic nationallicence Epistemic nationallicence Causal role function nationallicence Explanatory power nationallicence Axiomathes Springer Netherlands 25/1(2015-03-01), 5-22 1122-1151 25:1<5 2015 25 10516 https://doi.org/10.1007/s10516-014-9243-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10516-014-9243-x text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- van Eck Dingmar Ghent University, Centre for Logic and Philosophy of Science, Ghent, Belgium aut NATIONALLICENCE 773 0- Axiomathes Springer Netherlands 25/1(2015-03-01), 5-22 1122-1151 25:1<5 2015 25 10516