A competing risks approach to "biologic” interaction
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| 001 | 605476217 | ||
| 003 | CHVBK | ||
| 005 | 20210128100355.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20150401xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s10985-015-9318-z |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10985-015-9318-z | ||
| 245 | 0 | 2 | |a A competing risks approach to "biologic” interaction |h [Elektronische Daten] |c [Per Andersen, Anders Skrondal] |
| 520 | 3 | |a In epidemiology, the concepts of "biologic” and "statistical” interactions have been the subject of extensive debate. We present a new approach to biologic interaction based on Rothman's original (Am J Epidemiol, 104:587-592, 1976) discussion of sufficient causes. We do this in a probabilistic framework using competing risks and argue that sufficient cause interaction between two factors can be evaluated via the parameters in a particular statistical model, the additive hazard rate model. We present empirical conditions for presence of sufficient cause interaction and an example based on data from a liver cirrhosis trial illustrates the ideas. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Additive rate model |2 nationallicence | |
| 690 | 7 | |a Competing risks |2 nationallicence | |
| 690 | 7 | |a Interaction |2 nationallicence | |
| 690 | 7 | |a Monotonicity |2 nationallicence | |
| 690 | 7 | |a Necessary and sufficient causes |2 nationallicence | |
| 690 | 7 | |a Regression model |2 nationallicence | |
| 700 | 1 | |a Andersen |D Per |u Department of Biostatistics, University of Copenhagen, O. Farimagsgade 5, PB2099, 1014, Copenhagen K, Denmark |4 aut | |
| 700 | 1 | |a Skrondal |D Anders |u Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway |4 aut | |
| 773 | 0 | |t Lifetime Data Analysis |d Springer US; http://www.springer-ny.com |g 21/2(2015-04-01), 300-314 |x 1380-7870 |q 21:2<300 |1 2015 |2 21 |o 10985 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10985-015-9318-z |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10985-015-9318-z |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Andersen |D Per |u Department of Biostatistics, University of Copenhagen, O. Farimagsgade 5, PB2099, 1014, Copenhagen K, Denmark |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Skrondal |D Anders |u Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Lifetime Data Analysis |d Springer US; http://www.springer-ny.com |g 21/2(2015-04-01), 300-314 |x 1380-7870 |q 21:2<300 |1 2015 |2 21 |o 10985 | ||