caa a22 4500 605476284 CHVBK 20210128100355.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10985-014-9310-z doi (NATIONALLICENCE)springer-10.1007/s10985-014-9310-z Estimation and assessment of markov multistate models with intermittent observations on individuals [Elektronische Daten] [J. Lawless, N. Nazeri Rad] Multistate models provide important methods of analysis for many life history processes, and this is an area where John Klein made numerous contributions. When individuals in a study group are observed continuously so that all transitions between states, and their times, are known, estimation and model checking is fairly straightforward. However, individuals in many studies are observed intermittently, and only the states occupied at the observation times are known. We review methods of estimation and assessment for Markov models in this situation. Numerical studies that show the effects of inter-observation times are provided, and new methods for assessing fit are given. An illustration involving viral load dynamics for HIV-positive persons is presented. Springer Science+Business Media New York, 2014 Goodness of fit nationallicence Maximum likelihood nationallicence Panel data nationallicence Prevalence probability nationallicence Relative efficiency nationallicence Transition intensity nationallicence Transition probability nationallicence Lawless J. Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, N2L 3G1, Waterloo, ON, Canada aut Nazeri Rad N. Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, N2L 3G1, Waterloo, ON, Canada aut Lifetime Data Analysis Springer US; http://www.springer-ny.com 21/2(2015-04-01), 160-179 1380-7870 21:2<160 2015 21 10985 https://doi.org/10.1007/s10985-014-9310-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10985-014-9310-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lawless J. Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, N2L 3G1, Waterloo, ON, Canada aut NATIONALLICENCE 700 1- Nazeri Rad N. Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, N2L 3G1, Waterloo, ON, Canada aut NATIONALLICENCE 773 0- Lifetime Data Analysis Springer US; http://www.springer-ny.com 21/2(2015-04-01), 160-179 1380-7870 21:2<160 2015 21 10985