Development of children born to mothers with mental health problems: subcortical volumes and cognitive performance at 4½years

Verfasser / Beitragende:
[Astrid Bjørnebekk, Torill Siqveland, Kristin Haabrekke, Vibeke Moe, Kari Slinning, Anders Fjell, Kristine Walhovd]
Ort, Verlag, Jahr:
2015
Enthalten in:
European Child & Adolescent Psychiatry, 24/1(2015-01-01), 115-118
Format:
Artikel (online)
ID: 605476306
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024 7 0 |a 10.1007/s00787-014-0625-9  |2 doi 
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245 0 0 |a Development of children born to mothers with mental health problems: subcortical volumes and cognitive performance at 4½years  |h [Elektronische Daten]  |c [Astrid Bjørnebekk, Torill Siqveland, Kristin Haabrekke, Vibeke Moe, Kari Slinning, Anders Fjell, Kristine Walhovd] 
520 3 |a In a prospective longitudinal study, we investigated the outcomes of children born to mothers clinically referred for mental health problems during pregnancy (risk group, n=17) relative to a control group (n=31). Child cognitive functioning, and for subgroups (n=10+17), brain morphometry as derived from Magnetic resonance imaging (MRI), was measured at 4½years. Cognitive data included abstract visuospatial reasoning/problem solving and verbal scores. Subcortical regions of interest included the amygdala, accumbens area, hippocampus, caudate and putamen, chosen because their development seems potentially sensitive to an adverse intrauterine milieu and environmental experiences, and also due to their implication in cognitive and emotional processes. The risk group exhibited poorer abstract reasoning scores than the control group. No differences were found for verbal scores. MRI revealed smaller putamen volume in children in the risk group. Irrespective of group, putamen volume was positively related to visuospatial reasoning performance. Our results suggest that maternal psychopathology may be associated with child putamen development, nonverbal reasoning and problem solving skills. 
540 |a Springer-Verlag Berlin Heidelberg, 2014 
690 7 |a Maternal psychopathology  |2 nationallicence 
690 7 |a Neuroimaging  |2 nationallicence 
690 7 |a Cognitive development  |2 nationallicence 
690 7 |a Brain morphology  |2 nationallicence 
690 7 |a Abstract reasoning  |2 nationallicence 
690 7 |a Putamen  |2 nationallicence 
700 1 |a Bjørnebekk  |D Astrid  |u Department of Psychology, Research Group for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway  |4 aut 
700 1 |a Siqveland  |D Torill  |u Department of Psychology, University of Oslo, Oslo, Norway  |4 aut 
700 1 |a Haabrekke  |D Kristin  |u Department of Psychology, University of Oslo, Oslo, Norway  |4 aut 
700 1 |a Moe  |D Vibeke  |u Department of Psychology, University of Oslo, Oslo, Norway  |4 aut 
700 1 |a Slinning  |D Kari  |u Department of Psychology, University of Oslo, Oslo, Norway  |4 aut 
700 1 |a Fjell  |D Anders  |u Department of Psychology, Research Group for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway  |4 aut 
700 1 |a Walhovd  |D Kristine  |u Department of Psychology, Research Group for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway  |4 aut 
773 0 |t European Child & Adolescent Psychiatry  |d Springer Berlin Heidelberg  |g 24/1(2015-01-01), 115-118  |x 1018-8827  |q 24:1<115  |1 2015  |2 24  |o 787 
856 4 0 |u https://doi.org/10.1007/s00787-014-0625-9  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00787-014-0625-9  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bjørnebekk  |D Astrid  |u Department of Psychology, Research Group for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Siqveland  |D Torill  |u Department of Psychology, University of Oslo, Oslo, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Haabrekke  |D Kristin  |u Department of Psychology, University of Oslo, Oslo, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Moe  |D Vibeke  |u Department of Psychology, University of Oslo, Oslo, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Slinning  |D Kari  |u Department of Psychology, University of Oslo, Oslo, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fjell  |D Anders  |u Department of Psychology, Research Group for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Walhovd  |D Kristine  |u Department of Psychology, Research Group for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t European Child & Adolescent Psychiatry  |d Springer Berlin Heidelberg  |g 24/1(2015-01-01), 115-118  |x 1018-8827  |q 24:1<115  |1 2015  |2 24  |o 787