caa a22 4500 605476489 CHVBK 20210128100356.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00787-015-0681-9 doi (NATIONALLICENCE)springer-10.1007/s00787-015-0681-9 Epidemiology of child psychopathology: major milestones [Elektronische Daten] [Frank Verhulst, Henning Tiemeier] Child psychiatric epidemiology has developed rapidly from descriptive, cross-sectional studies in the 1960s to the current large-scale prospective cohorts that unravel aetiological mechanisms. The objective of the study was to give an overview of epidemiological studies that have influenced child psychiatry. A chronological overview of selected major milestone studies was obtained to demonstrate the development of child psychiatric epidemiology, with a more in-depth discussion of findings and methodological issues exemplified in one cohort, the Generation R Study. Epidemiological studies have been successful in describing the frequency and course of child psychiatric problems. The high expectations that biological factors can be used to better explain, diagnose or predict child psychiatric problems have not been met. More ambitious large-scale child psychiatric cohort studies are needed, carefully applying genetics, neuroscience or other molecular research to better understand how the brain produces maladaptive behaviour. Progress will only be attained if the basic sciences are systematically integrated in cohorts with rigorous epidemiological designs rather than hurriedly inserted in child psychiatric studies. The Author(s), 2015 Epidemiology nationallicence Child psychiatry nationallicence Methodology nationallicence Longitudinal nationallicence Cohort nationallicence Prenatal nationallicence Verhulst Frank Department of Child and Adolescent Psychiatry, Erasmus Medical Center-Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands aut Tiemeier Henning Department of Child and Adolescent Psychiatry, Erasmus Medical Center-Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands aut European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/6(2015-06-01), 607-617 1018-8827 24:6<607 2015 24 787 https://doi.org/10.1007/s00787-015-0681-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00787-015-0681-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Verhulst Frank Department of Child and Adolescent Psychiatry, Erasmus Medical Center-Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Tiemeier Henning Department of Child and Adolescent Psychiatry, Erasmus Medical Center-Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands aut NATIONALLICENCE 773 0- European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/6(2015-06-01), 607-617 1018-8827 24:6<607 2015 24 787