caa a22 4500 605476578 CHVBK 20210128100357.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00787-014-0658-0 doi (NATIONALLICENCE)springer-10.1007/s00787-014-0658-0 Childhood neurodevelopmental problems and adolescent bully victimization: population-based, prospective twin study in Sweden [Elektronische Daten] [Peggy Törn, Erik Pettersson, Paul Lichtenstein, Henrik Anckarsäter, Sebastian Lundström, Clara Hellner Gumpert, Henrik Larsson, Linnea Kollberg, Niklas Långström, Linda Halldner] Bully victimization is a common problem among children with neurodevelopmental disorders, including attention deficit/hyperactivity disorder and autism spectrum disorder. Previous research was mostly cross-sectional and seldom accounted for co-morbid psychopathology, which makes it difficult to draw conclusions about causality and specificity of any association. Using a genetically informative prospective design, we investigated the association between various neurodevelopmental problems (NDPs) in childhood and bully victimization in adolescence, and the relative contributions of genetic and environmental factors to this association. We obtained parent-reports of NDPs at age 9/12 years and self-reported bully victimization at age 15 for 3,921 children participating in the The Child and Adolescent Twin Study in Sweden (CATSS). Structural equation modelling was used to control for NDP co-morbidity and bully victimization at baseline. Cholesky decomposition was used to analyse genetic and environmental contributions to observed associations. Because most of the NDPs were associated to later bully victimization, a common effect of all NDPs was summarized into a general NDP factor. Controlling for this general factor, only problems with social interaction and motor control uniquely predicted subsequent bully victimization in girls. General and unique associations were influenced by both genetic and unique environmental factors. NDPs in general and social interaction and motor problems in particular predicted later bully victimization. The longitudinal design and twin analyses indicated that these associations might be causal. Knowledge of these vulnerabilities may be important when designing risk assessment and prevention strategies. Springer-Verlag Berlin Heidelberg, 2015 Bully victimization nationallicence Neurodevelopmental problems nationallicence Neuropsychiatry nationallicence General factor nationallicence Törn Peggy Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut Pettersson Erik Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut Lichtenstein Paul Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut Anckarsäter Henrik Centre for Ethics, Law and Mental Health (CELAM), University of Gothenburg, Gothenburg, Sweden aut Lundström Sebastian Centre for Ethics, Law and Mental Health (CELAM), University of Gothenburg, Gothenburg, Sweden aut Hellner Gumpert Clara Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden aut Larsson Henrik Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut Kollberg Linnea Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut Långström Niklas Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut Halldner Linda Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/9(2015-09-01), 1049-1059 1018-8827 24:9<1049 2015 24 787 https://doi.org/10.1007/s00787-014-0658-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00787-014-0658-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Törn Peggy Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Pettersson Erik Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Lichtenstein Paul Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Anckarsäter Henrik Centre for Ethics, Law and Mental Health (CELAM), University of Gothenburg, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Lundström Sebastian Centre for Ethics, Law and Mental Health (CELAM), University of Gothenburg, Gothenburg, Sweden aut NATIONALLICENCE 700 1- Hellner Gumpert Clara Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Larsson Henrik Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Kollberg Linnea Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Långström Niklas Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Halldner Linda Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 773 0- European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/9(2015-09-01), 1049-1059 1018-8827 24:9<1049 2015 24 787