caa a22 4500 605476624 CHVBK 20210128100357.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00787-014-0659-z doi (NATIONALLICENCE)springer-10.1007/s00787-014-0659-z Quality of life in children with OCD before and after treatment [Elektronische Daten] [Bernhard Weidle, Tord Ivarsson, Per Thomsen, Stian Lydersen, Thomas Jozefiak] Quality of life (QoL) is a well-established outcome measure. In contrast to adult obsessive-compulsive disorder (OCD), little is known about the effects of treatment on QoL in children with OCD. This study aimed to assess QoL after cognitive behavioural therapy (CBT) in children and adolescents with OCD compared with the general population and to explore factors associated with potential changes in QoL after treatment. QoL was assessed in 135 children and adolescents (ages 7-17; mean 13 [SD 2.7] years; 48.1% female) before and after 14 CBT sessions, using self-report and a caregivers proxy report of the Questionnaire for Measuring Health-related Quality of Life in Children and Adolescents (KINDL-R). QoL was compared with an age- and gender-matched sample from the general population. Before treatment, QoL was markedly lower in children with OCD compared with the general population. QoL improved significantly in CBT responders (mean score change 7.4), to the same range as QoL in the general population. Non-responders reported no QoL changes after treatment, except for one patient. Comorbidity, family accommodation and psychosocial functioning were not associated with changes in QoL after treatment. To our knowledge, this is the first study of the changes in QoL after treatment of paediatric OCD. The assessment of QoL beyond symptoms and function in children with OCD has been shown to be reliable and informative. The results of this study support the application of QoL assessment as an additional measure of treatment outcome in children and adolescents with OCD. Springer-Verlag Berlin Heidelberg, 2014 Paediatric OCD nationallicence Quality of life nationallicence Comorbidity nationallicence Cognitive behavioural therapy nationallicence Assessment nationallicence Weidle Bernhard Department of Child and Adolescent Psychiatry, St.Olavs University Hospital, Elgeseter, Post box 6810, 7433, Trondheim, Norway aut Ivarsson Tord Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Gullhaugveien 1-3, 0484, Oslo, Norway aut Thomsen Per Psychiatric Hospital for Children and Adolescents, University Hospital in Aarhus, Aarhus, Denmark aut Lydersen Stian Faculty of Medicine, Regional Centre for Child and Youth Mental Health and Child Welfare, Norwegian University of Science and Technology, Trondheim, Norway aut Jozefiak Thomas Department of Child and Adolescent Psychiatry, St.Olavs University Hospital, Elgeseter, Post box 6810, 7433, Trondheim, Norway aut European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/9(2015-09-01), 1061-1074 1018-8827 24:9<1061 2015 24 787 https://doi.org/10.1007/s00787-014-0659-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00787-014-0659-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Weidle Bernhard Department of Child and Adolescent Psychiatry, St.Olavs University Hospital, Elgeseter, Post box 6810, 7433, Trondheim, Norway aut NATIONALLICENCE 700 1- Ivarsson Tord Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Gullhaugveien 1-3, 0484, Oslo, Norway aut NATIONALLICENCE 700 1- Thomsen Per Psychiatric Hospital for Children and Adolescents, University Hospital in Aarhus, Aarhus, Denmark aut NATIONALLICENCE 700 1- Lydersen Stian Faculty of Medicine, Regional Centre for Child and Youth Mental Health and Child Welfare, Norwegian University of Science and Technology, Trondheim, Norway aut NATIONALLICENCE 700 1- Jozefiak Thomas Department of Child and Adolescent Psychiatry, St.Olavs University Hospital, Elgeseter, Post box 6810, 7433, Trondheim, Norway aut NATIONALLICENCE 773 0- European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/9(2015-09-01), 1061-1074 1018-8827 24:9<1061 2015 24 787