Salivary oxytocin in adolescents with conduct problems and callous-unemotional traits
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| 024 | 7 | 0 | |a 10.1007/s00787-015-0765-6 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00787-015-0765-6 | ||
| 245 | 0 | 0 | |a Salivary oxytocin in adolescents with conduct problems and callous-unemotional traits |h [Elektronische Daten] |c [Tomer Levy, Yuval Bloch, Meytal Bar-Maisels, Galia Gat-Yablonski, Amir Djalovski, Katy Borodkin, Alan Apter] |
| 520 | 3 | |a Callous-unemotional (CU) traits correlate with the severity and prognosis of conduct disorder in youth. The neuropeptide oxytocin (OT) has been linked to prosocial behaviors, including empathy and collaboration with others. This study discusses a possible role for OT in the biology of delinquent behavior. We hypothesized that in delinquent youth OT secretion will correlate with the severity of conduct problems and specifically with the level of CU traits. The study group included 67 male adolescents (mean age 16.2years) undergoing residential treatment, previously assessed by an open clinical interview and history for the psychiatric diagnosis. Staff based Inventory of Callous-Unemotional traits for psychopathy and Strength and Difficulties Questionnaire were administered, and patients' medical and social personal files were systematically coded for previous history of antisocial acts using the Brown-Goodwin Questionnaire. Salivary OT was assayed by ELISA. Salivary OT levels were inversely correlated with conduct problems severity on Strength and Difficulties Questionnaire (r=−0.27; p≤0.01). Recorded history of antisocial acts did not correlate with current OT levels. Odds ratio (OR) for significant CU traits among subjects with conduct problems was increased in low-OT (OR=14, p≤0.05) but not in high-OT subjects (OR=6, p≥0.05). Children with conduct problems and low levels of salivary OT are at risk for significant CU traits. These results suggest a possible role for salivary OT as a biomarker for CU traits and conduct problems severity. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2015 | ||
| 690 | 7 | |a Oxytocin |2 nationallicence | |
| 690 | 7 | |a Conduct Disorder |2 nationallicence | |
| 690 | 7 | |a Psychopathy |2 nationallicence | |
| 690 | 7 | |a Callous-Unemotional traits, adolescents |2 nationallicence | |
| 690 | 7 | |a BGQ : Brown Goodwin questionnaire |2 nationallicence | |
| 690 | 7 | |a CD : Conduct disorder |2 nationallicence | |
| 690 | 7 | |a CP : Conduct problems |2 nationallicence | |
| 690 | 7 | |a CU : Callous-unemotional |2 nationallicence | |
| 690 | 7 | |a ICU : Inventory of callous-unemotional traits |2 nationallicence | |
| 690 | 7 | |a OT : Oxytocin |2 nationallicence | |
| 690 | 7 | |a OXTR : Oxytocin receptor |2 nationallicence | |
| 690 | 7 | |a SDQ : Strength and difficulties questionnaire |2 nationallicence | |
| 690 | 7 | |a SNP : Single nucleotide polymorphism |2 nationallicence | |
| 700 | 1 | |a Levy |D Tomer |u Department of Child and Adolescent Psychiatry, Shalvata Mental Health Center, 45100, Hod Hasharon, Israel |4 aut | |
| 700 | 1 | |a Bloch |D Yuval |u Department of Child and Adolescent Psychiatry, Shalvata Mental Health Center, 45100, Hod Hasharon, Israel |4 aut | |
| 700 | 1 | |a Bar-Maisels |D Meytal |u Sackler Faculty of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel |4 aut | |
| 700 | 1 | |a Gat-Yablonski |D Galia |u Sackler Faculty of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel |4 aut | |
| 700 | 1 | |a Djalovski |D Amir |u Department of Psychology and The Gonda Brain Sciences Center, Bar-Ilan University, 52900, Ramat-Gan, Israel |4 aut | |
| 700 | 1 | |a Borodkin |D Katy |u Speech-Language-Hearing Sciences, Lehman College, The City University of New York, 10468, New York, NY, USA |4 aut | |
| 700 | 1 | |a Apter |D Alan |u Sackler Faculty of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel |4 aut | |
| 773 | 0 | |t European Child & Adolescent Psychiatry |d Springer Berlin Heidelberg |g 24/12(2015-12-01), 1543-1551 |x 1018-8827 |q 24:12<1543 |1 2015 |2 24 |o 787 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00787-015-0765-6 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00787-015-0765-6 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Levy |D Tomer |u Department of Child and Adolescent Psychiatry, Shalvata Mental Health Center, 45100, Hod Hasharon, Israel |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bloch |D Yuval |u Department of Child and Adolescent Psychiatry, Shalvata Mental Health Center, 45100, Hod Hasharon, Israel |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bar-Maisels |D Meytal |u Sackler Faculty of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gat-Yablonski |D Galia |u Sackler Faculty of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Djalovski |D Amir |u Department of Psychology and The Gonda Brain Sciences Center, Bar-Ilan University, 52900, Ramat-Gan, Israel |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Borodkin |D Katy |u Speech-Language-Hearing Sciences, Lehman College, The City University of New York, 10468, New York, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Apter |D Alan |u Sackler Faculty of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t European Child & Adolescent Psychiatry |d Springer Berlin Heidelberg |g 24/12(2015-12-01), 1543-1551 |x 1018-8827 |q 24:12<1543 |1 2015 |2 24 |o 787 | ||