Functional deterioration from the premorbid period to 2 years after the first episode of psychosis in early-onset psychosis
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| 024 | 7 | 0 | |a 10.1007/s00787-015-0693-5 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00787-015-0693-5 | ||
| 245 | 0 | 0 | |a Functional deterioration from the premorbid period to 2 years after the first episode of psychosis in early-onset psychosis |h [Elektronische Daten] |c [Ángel Del Rey-Mejías, David Fraguas, Covadonga Díaz-Caneja, Laura Pina-Camacho, Josefina Castro-Fornieles, Inmaculada Baeza, Ana Espliego, Jessica Merchán-Naranjo, Ana González-Pinto, Elena de la Serna, Beatriz Payá, Montserrat Graell, Celso Arango, Mara Parellada] |
| 520 | 3 | |a The aim of the study was to analyze changes in functional adjustment from childhood to 2years after the first episode of psychosis (FEP) in patients with early-onset schizophrenia spectrum disorders (SSD) and affective psychoses (AFP) and a good or intermediate level of premorbid adjustment. We followed 106 adolescents (aged 12-17years) with FEP for 2years after recruitment. Premorbid adjustment in childhood was assessed in 98 patients with the childhood subscale of the Cannon-Spoor Premorbid Adjustment Scale (c-PAS). Global functioning was assessed 2years after the FEP with the Children's Global Assessment Scale (c-GAS) or the Global Assessment of Functioning scale (GAF), as appropriate. Functional deterioration was defined as a downward shift in the level of functional adjustment from childhood to 2 years after the FEP. In patients with good or intermediate premorbid adjustment, functional deterioration was observed in 28.2% (26.5% of the AFP group, 29.4% of the SSD group). Longer duration of untreated psychosis (Beta=0.01; P=0.01) and higher symptom severity at the FEP, as measured with the Clinical Global Impression Scale (Beta=1.12; P=0.02), significantly predicted the presence of functional deterioration, accounting for 21.4% of the variance. Irrespective of diagnosis (SSD or AFP), almost one-third of adolescents with FEP and good or intermediate premorbid adjustment showed functional deterioration from the premorbid period to 2years after the FEP. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2015 | ||
| 690 | 7 | |a Premorbid adjustment |2 nationallicence | |
| 690 | 7 | |a Global functioning |2 nationallicence | |
| 690 | 7 | |a Duration of untreated psychosis |2 nationallicence | |
| 690 | 7 | |a First-episode psychosis |2 nationallicence | |
| 690 | 7 | |a Schizophrenia |2 nationallicence | |
| 690 | 7 | |a Affective psychosis |2 nationallicence | |
| 690 | 7 | |a Early-onset psychosis |2 nationallicence | |
| 700 | 1 | |a Del Rey-Mejías |D Ángel |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | |
| 700 | 1 | |a Fraguas |D David |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | |
| 700 | 1 | |a Díaz-Caneja |D Covadonga |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | |
| 700 | 1 | |a Pina-Camacho |D Laura |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | |
| 700 | 1 | |a Castro-Fornieles |D Josefina |u Department of Child and Adolescent Psychiatry and Psychology, SGR-489CIBERSAM. Institute Clinic of Neurosciences, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain |4 aut | |
| 700 | 1 | |a Baeza |D Inmaculada |u Department of Child and Adolescent Psychiatry and Psychology, SGR-489CIBERSAM. Institute Clinic of Neurosciences, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain |4 aut | |
| 700 | 1 | |a Espliego |D Ana |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | |
| 700 | 1 | |a Merchán-Naranjo |D Jessica |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | |
| 700 | 1 | |a González-Pinto |D Ana |u Mood Disorders Research Center, 03-RC-003, Hospital Santiago Apóstol, CIBERSAM, Vitoria, Spain |4 aut | |
| 700 | 1 | |a de la Serna |D Elena |u Department of Child and Adolescent Psychiatry and Psychology, SGR-489CIBERSAM. Institute Clinic of Neurosciences, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain |4 aut | |
| 700 | 1 | |a Payá |D Beatriz |u Department of Child Psychiatry, Hospital Universitario Marqués de Valdecilla, CIBERSAM, Santander, Spain |4 aut | |
| 700 | 1 | |a Graell |D Montserrat |u Section of Child and Adolescent Psychiatry and Psychology, Hospital Infantil Universitario Niño Jesus, CIBERSAM, Madrid, Spain |4 aut | |
| 700 | 1 | |a Arango |D Celso |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | |
| 700 | 1 | |a Parellada |D Mara |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | |
| 773 | 0 | |t European Child & Adolescent Psychiatry |d Springer Berlin Heidelberg |g 24/12(2015-12-01), 1447-1459 |x 1018-8827 |q 24:12<1447 |1 2015 |2 24 |o 787 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00787-015-0693-5 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00787-015-0693-5 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Del Rey-Mejías |D Ángel |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fraguas |D David |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Díaz-Caneja |D Covadonga |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Pina-Camacho |D Laura |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Castro-Fornieles |D Josefina |u Department of Child and Adolescent Psychiatry and Psychology, SGR-489CIBERSAM. Institute Clinic of Neurosciences, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Baeza |D Inmaculada |u Department of Child and Adolescent Psychiatry and Psychology, SGR-489CIBERSAM. Institute Clinic of Neurosciences, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Espliego |D Ana |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Merchán-Naranjo |D Jessica |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a González-Pinto |D Ana |u Mood Disorders Research Center, 03-RC-003, Hospital Santiago Apóstol, CIBERSAM, Vitoria, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a de la Serna |D Elena |u Department of Child and Adolescent Psychiatry and Psychology, SGR-489CIBERSAM. Institute Clinic of Neurosciences, IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Payá |D Beatriz |u Department of Child Psychiatry, Hospital Universitario Marqués de Valdecilla, CIBERSAM, Santander, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Graell |D Montserrat |u Section of Child and Adolescent Psychiatry and Psychology, Hospital Infantil Universitario Niño Jesus, CIBERSAM, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Arango |D Celso |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Parellada |D Mara |u Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43, 28009, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t European Child & Adolescent Psychiatry |d Springer Berlin Heidelberg |g 24/12(2015-12-01), 1447-1459 |x 1018-8827 |q 24:12<1447 |1 2015 |2 24 |o 787 | ||