caa a22 4500 605477035 CHVBK 20210128100359.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00787-014-0592-1 doi (NATIONALLICENCE)springer-10.1007/s00787-014-0592-1 Treatment moderators of cognitive behavior therapy to reduce aggressive behavior: a meta-analysis [Elektronische Daten] [Kirsten Smeets, Anouk Leeijen, Mariët van der Molen, Floor Scheepers, Jan Buitelaar, Nanda Rommelse] Maladaptive aggression in adolescents is an increasing public health concern. Cognitive Behavior Therapy (CBT) is one of the most common and promising treatments of aggression. However, there is a lack of information on predictors of treatment response regarding CBT. Therefore, a meta-analysis was performed examining the role of predictors on treatment response of CBT. Twenty-five studies were evaluated (including 2,302 participants; 1,580 boys and 722 girls), and retrieved through searches on PubMed, PsycINFO and EMBASE. Effect sizes were calculated for studies that met inclusion criteria. Study population differences and specific CBT characteristics were examined for their explanatory power. There was substantial variation across studies in design and outcome variables. The meta-analysis showed a medium treatment effect for CBT to reduce aggression (Cohen'd=0.50). No predictors of treatment response were found in the meta-analysis. Only two studies did examine whether proactive versus reactive aggression could be a moderator of treatment outcome, and no effect was found of this subtyping of aggression. These study results suggest that CBT is effective in reducing maladaptive aggression. Furthermore, treatment setting and duration did not seem to influence treatment effect, which shows the need for development of more cost-effective and less-invasive interventions. More research is needed on moderators of outcome of CBT, including proactive versus reactive aggression. This requires better standardization of design, predictors, and outcome measures across studies. Springer-Verlag Berlin Heidelberg, 2014 Aggression nationallicence Cognitive behavior therapy nationallicence Meta-analysis nationallicence Effect size nationallicence Smeets Kirsten Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands aut Leeijen Anouk Department of Health Sciences, VU University Amsterdam, Amsterdam, The Netherlands aut van der Molen Mariët Faculty of Psychology and Education and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands aut Scheepers Floor Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, UMC Utrecht, Utrecht, The Netherlands aut Buitelaar Jan Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands aut Rommelse Nanda Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands aut European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/3(2015-03-01), 255-264 1018-8827 24:3<255 2015 24 787 https://doi.org/10.1007/s00787-014-0592-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00787-014-0592-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Smeets Kirsten Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands aut NATIONALLICENCE 700 1- Leeijen Anouk Department of Health Sciences, VU University Amsterdam, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- van der Molen Mariët Faculty of Psychology and Education and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Scheepers Floor Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, UMC Utrecht, Utrecht, The Netherlands aut NATIONALLICENCE 700 1- Buitelaar Jan Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands aut NATIONALLICENCE 700 1- Rommelse Nanda Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands aut NATIONALLICENCE 773 0- European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/3(2015-03-01), 255-264 1018-8827 24:3<255 2015 24 787