Antipsychotic prescribing in youths: a French community-based study from 2006 to 2013

Verfasser / Beitragende:
[Hélène Verdoux, Elodie Pambrun, Sébastien Cortaredona, Marie Tournier, Pierre Verger]
Ort, Verlag, Jahr:
2015
Enthalten in:
European Child & Adolescent Psychiatry, 24/10(2015-10-01), 1181-1191
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00787-014-0668-y  |2 doi 
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245 0 0 |a Antipsychotic prescribing in youths: a French community-based study from 2006 to 2013  |h [Elektronische Daten]  |c [Hélène Verdoux, Elodie Pambrun, Sébastien Cortaredona, Marie Tournier, Pierre Verger] 
520 3 |a The objectives were to explore in a community-based sample of persons aged 0-25years: (1) trends in antipsychotic prescribing, (2) characteristics of the zone of residence associated with antipsychotic prescribing rates, and (3) the pattern of antipsychotic prescribing. The study was performed using reimbursement data from the French Insurance Healthcare system. Prescribing trends were investigated over the period 2006-2013. An ecological design was used to assess the impact of the socio-economical and health resource characteristics of the zone of residence (n=96 administrative subdivisions of French territory) on antipsychotic prescribing rates. The pattern of antipsychotic prescribing was explored in a cohort of youths newly treated with antipsychotics. Over the period 2006-2013, antipsychotic dispensing rates were stable in persons aged 0-25years (4.8 per 1,000 in 2006 and 4.9 per 1,000 in 2013). First-generation antipsychotic dispensing rates decreased from 3.1 to 2.6 per 1,000 (OR=0.96, 95% CI 0.94-0.98), while second-generation antipsychotic dispensing rates increased from 2.7 to 3.4 per 1,000 (OR=1.03, 95% CI 1.01-1.05). Antipsychotic prescribing rates were impacted by health resource characteristics of the zone of residence in children aged 10years and under and by socio-economical characteristics in those aged 16-20years. In all the age groups, antipsychotics were principally started by hospital practitioners (47%) and general practitioners (34%). The rates of psychostimulants concomitantly prescribed with antipsychotics were lower than 5%. In conclusion, rates of youths exposed to second-generation antipsychotics are still rising. The impact of environmental characteristics on antipsychotics prescribing and appropriateness of these prescriptions in youths should be further investigated. 
540 |a Springer-Verlag Berlin Heidelberg, 2015 
690 7 |a Children  |2 nationallicence 
690 7 |a Adolescents  |2 nationallicence 
690 7 |a Antipsychotics  |2 nationallicence 
690 7 |a Prescribing trends  |2 nationallicence 
690 7 |a Community characteristics  |2 nationallicence 
700 1 |a Verdoux  |D Hélène  |u Univ. Bordeaux, U657, 33000, Bordeaux, France  |4 aut 
700 1 |a Pambrun  |D Elodie  |u Univ. Bordeaux, U657, 33000, Bordeaux, France  |4 aut 
700 1 |a Cortaredona  |D Sébastien  |u Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, INSERM, IRD), Marseille, France  |4 aut 
700 1 |a Tournier  |D Marie  |u Univ. Bordeaux, U657, 33000, Bordeaux, France  |4 aut 
700 1 |a Verger  |D Pierre  |u Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, INSERM, IRD), Marseille, France  |4 aut 
773 0 |t European Child & Adolescent Psychiatry  |d Springer Berlin Heidelberg  |g 24/10(2015-10-01), 1181-1191  |x 1018-8827  |q 24:10<1181  |1 2015  |2 24  |o 787 
856 4 0 |u https://doi.org/10.1007/s00787-014-0668-y  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Verdoux  |D Hélène  |u Univ. Bordeaux, U657, 33000, Bordeaux, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pambrun  |D Elodie  |u Univ. Bordeaux, U657, 33000, Bordeaux, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Cortaredona  |D Sébastien  |u Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, INSERM, IRD), Marseille, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tournier  |D Marie  |u Univ. Bordeaux, U657, 33000, Bordeaux, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Verger  |D Pierre  |u Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, INSERM, IRD), Marseille, France  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t European Child & Adolescent Psychiatry  |d Springer Berlin Heidelberg  |g 24/10(2015-10-01), 1181-1191  |x 1018-8827  |q 24:10<1181  |1 2015  |2 24  |o 787