caa a22 4500 605477116 CHVBK 20210128100359.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00787-014-0668-y doi (NATIONALLICENCE)springer-10.1007/s00787-014-0668-y Antipsychotic prescribing in youths: a French community-based study from 2006 to 2013 [Elektronische Daten] [Hélène Verdoux, Elodie Pambrun, Sébastien Cortaredona, Marie Tournier, Pierre Verger] The objectives were to explore in a community-based sample of persons aged 0-25years: (1) trends in antipsychotic prescribing, (2) characteristics of the zone of residence associated with antipsychotic prescribing rates, and (3) the pattern of antipsychotic prescribing. The study was performed using reimbursement data from the French Insurance Healthcare system. Prescribing trends were investigated over the period 2006-2013. An ecological design was used to assess the impact of the socio-economical and health resource characteristics of the zone of residence (n=96 administrative subdivisions of French territory) on antipsychotic prescribing rates. The pattern of antipsychotic prescribing was explored in a cohort of youths newly treated with antipsychotics. Over the period 2006-2013, antipsychotic dispensing rates were stable in persons aged 0-25years (4.8 per 1,000 in 2006 and 4.9 per 1,000 in 2013). First-generation antipsychotic dispensing rates decreased from 3.1 to 2.6 per 1,000 (OR=0.96, 95% CI 0.94-0.98), while second-generation antipsychotic dispensing rates increased from 2.7 to 3.4 per 1,000 (OR=1.03, 95% CI 1.01-1.05). Antipsychotic prescribing rates were impacted by health resource characteristics of the zone of residence in children aged 10years and under and by socio-economical characteristics in those aged 16-20years. In all the age groups, antipsychotics were principally started by hospital practitioners (47%) and general practitioners (34%). The rates of psychostimulants concomitantly prescribed with antipsychotics were lower than 5%. In conclusion, rates of youths exposed to second-generation antipsychotics are still rising. The impact of environmental characteristics on antipsychotics prescribing and appropriateness of these prescriptions in youths should be further investigated. Springer-Verlag Berlin Heidelberg, 2015 Children nationallicence Adolescents nationallicence Antipsychotics nationallicence Prescribing trends nationallicence Community characteristics nationallicence Verdoux Hélène Univ. Bordeaux, U657, 33000, Bordeaux, France aut Pambrun Elodie Univ. Bordeaux, U657, 33000, Bordeaux, France aut Cortaredona Sébastien Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, INSERM, IRD), Marseille, France aut Tournier Marie Univ. Bordeaux, U657, 33000, Bordeaux, France aut Verger Pierre Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, INSERM, IRD), Marseille, France aut European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/10(2015-10-01), 1181-1191 1018-8827 24:10<1181 2015 24 787 https://doi.org/10.1007/s00787-014-0668-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00787-014-0668-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Verdoux Hélène Univ. Bordeaux, U657, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Pambrun Elodie Univ. Bordeaux, U657, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Cortaredona Sébastien Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, INSERM, IRD), Marseille, France aut NATIONALLICENCE 700 1- Tournier Marie Univ. Bordeaux, U657, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Verger Pierre Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, INSERM, IRD), Marseille, France aut NATIONALLICENCE 773 0- European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/10(2015-10-01), 1181-1191 1018-8827 24:10<1181 2015 24 787