Minor neurodevelopmental impairments are associated with increased occurrence of ADHD symptoms in children born extremely preterm

Verfasser / Beitragende:
[Silje Elgen, Kristian Sommerfelt, Katrine Leversen, Trond Markestad]
Ort, Verlag, Jahr:
2015
Enthalten in:
European Child & Adolescent Psychiatry, 24/4(2015-04-01), 463-470
Format:
Artikel (online)
ID: 605477264
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024 7 0 |a 10.1007/s00787-014-0597-9  |2 doi 
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245 0 0 |a Minor neurodevelopmental impairments are associated with increased occurrence of ADHD symptoms in children born extremely preterm  |h [Elektronische Daten]  |c [Silje Elgen, Kristian Sommerfelt, Katrine Leversen, Trond Markestad] 
520 3 |a ADHD is more common in children born preterm than at term. The purpose of the study was to examine if, and to what extent, ADHD symptoms are associated with minor neurodevelopmental impairments (NDI) in extremely preterm children. In a national population-based cohort with gestational age 22-27weeks or birth weight <1,000g assessed at 5years of age, scores on Yale Children's Inventory (YCI) scales (seven scales) were related to normal functions vs. NDI defined as mild impairments in cognitive function (IQ 70-84), motor function (Movement Assessment Battery for children score > the 95th percentile or freely ambulatory cerebral palsy), vision (correctable), and hearing (no hearing aid). YCI was completed for 213 of 258 eligible children (83%). Children with minor NDIs (n=98) had significantly higher scores (more ADHD symptoms) than those without NDI (n=115) on the YCI scales of Attention, Tractability, Adaptability and Total score. Increasing numbers of minor NDIs were associated with higher mean YCI scores. In multivariate analysis only decreased hearing, IQ, and male gender were significantly associated with scores on the Attention scale. Thirty-three children (16%) had scores >3 on the Attention scale (probably ADHD), and the proportion was significantly higher for those with mild NDIs compared to those without (Odds ratio=2.7, 95% CI 1.3-6.0). Children born extremely preterm with minor NDIs were more likely to have ADHD symptoms than those with no NDI, and increasing number of minor NDIs were associated with more ADHD symptoms. 
540 |a Springer-Verlag Berlin Heidelberg, 2014 
690 7 |a Extremely preterm infants  |2 nationallicence 
690 7 |a Attention deficit hyperactivity disorder  |2 nationallicence 
690 7 |a Neurodevelopmental impairment  |2 nationallicence 
690 7 |a Mental health  |2 nationallicence 
700 1 |a Elgen  |D Silje  |u Department of Clinical Medicine, University of Bergen, 5021, Bergen, Norway  |4 aut 
700 1 |a Sommerfelt  |D Kristian  |u Department of Clinical Medicine, University of Bergen, 5021, Bergen, Norway  |4 aut 
700 1 |a Leversen  |D Katrine  |u Department of Pediatrics, Haukeland University Hospital, Bergen, Norway  |4 aut 
700 1 |a Markestad  |D Trond  |u Department of Clinical Medicine, University of Bergen, 5021, Bergen, Norway  |4 aut 
773 0 |t European Child & Adolescent Psychiatry  |d Springer Berlin Heidelberg  |g 24/4(2015-04-01), 463-470  |x 1018-8827  |q 24:4<463  |1 2015  |2 24  |o 787 
856 4 0 |u https://doi.org/10.1007/s00787-014-0597-9  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00787-014-0597-9  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Elgen  |D Silje  |u Department of Clinical Medicine, University of Bergen, 5021, Bergen, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sommerfelt  |D Kristian  |u Department of Clinical Medicine, University of Bergen, 5021, Bergen, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Leversen  |D Katrine  |u Department of Pediatrics, Haukeland University Hospital, Bergen, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Markestad  |D Trond  |u Department of Clinical Medicine, University of Bergen, 5021, Bergen, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t European Child & Adolescent Psychiatry  |d Springer Berlin Heidelberg  |g 24/4(2015-04-01), 463-470  |x 1018-8827  |q 24:4<463  |1 2015  |2 24  |o 787