caa a22 4500 605477361 CHVBK 20210128100400.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00787-014-0643-7 doi (NATIONALLICENCE)springer-10.1007/s00787-014-0643-7 Parental migration and Asperger's syndrome [Elektronische Daten] [Venla Lehti, Keely Cheslack-Postava, Mika Gissler, Susanna Hinkka-Yli-Salomäki, Alan Brown, Andre Sourander] Parental immigration has been suggested as a possible risk factor for autism spectrum disorders (ASD), but findings have been inconsistent. Very few studies have focused specifically on Asperger's syndrome. The aim of this study was to examine the association between maternal and paternal immigration and the diagnosis of Asperger's syndrome in offspring. The study was a nested case-control study based on a national birth cohort in Finland. Children born in 1987-2005 and diagnosed with Asperger's syndrome by the year 2007 were identified from the Finnish Hospital Discharge Register (N=1,783). Four matched controls for each case were selected from the Finnish Medical Birth Register (N=7,106). Information on maternal and paternal country of birth and mother tongue was collected from the Finnish Central Population Register. The study showed that children whose parents are both immigrants have a significantly lower likelihood of being diagnosed with Asperger's syndrome than those with two Finnish parents [adjusted odds ratio (aOR) 0.2, 95% confidence interval (CI) 0.1-0.4]. No significant associations were found between having only one immigrant parent and the diagnosis of Asperger's syndrome. A regional analysis showed a significantly decreased likelihood of the diagnosis of Asperger's syndrome in children whose mother (aOR 0.1, 95% CI 0.01-0.5) or father (aOR 0.2, 95% CI 0.05-0.5) was born in Sub-Saharan Africa. The findings may help in identifying risk factors for different ASD subtypes. On the other hand, they might reflect service use of immigrant families in Finland. Springer-Verlag Berlin Heidelberg, 2014 Autism nationallicence Asperger's syndrome nationallicence Risk factor nationallicence Parental nationallicence Migration nationallicence Lehti Venla Research Centre for Child Psychiatry, University of Turku, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland aut Cheslack-Postava Keely Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA aut Gissler Mika Research Centre for Child Psychiatry, University of Turku, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland aut Hinkka-Yli-Salomäki Susanna Research Centre for Child Psychiatry, University of Turku, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland aut Brown Alan Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA aut Sourander Andre Research Centre for Child Psychiatry, University of Turku, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland aut European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/8(2015-08-01), 941-948 1018-8827 24:8<941 2015 24 787 https://doi.org/10.1007/s00787-014-0643-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00787-014-0643-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lehti Venla Research Centre for Child Psychiatry, University of Turku, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland aut NATIONALLICENCE 700 1- Cheslack-Postava Keely Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA aut NATIONALLICENCE 700 1- Gissler Mika Research Centre for Child Psychiatry, University of Turku, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland aut NATIONALLICENCE 700 1- Hinkka-Yli-Salomäki Susanna Research Centre for Child Psychiatry, University of Turku, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland aut NATIONALLICENCE 700 1- Brown Alan Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA aut NATIONALLICENCE 700 1- Sourander Andre Research Centre for Child Psychiatry, University of Turku, Lemminkäisenkatu 3/Teutori, 20014, Turku, Finland aut NATIONALLICENCE 773 0- European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/8(2015-08-01), 941-948 1018-8827 24:8<941 2015 24 787