caa a22 4500 605477450 CHVBK 20210128100401.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1007/s00787-014-0602-3 doi (NATIONALLICENCE)springer-10.1007/s00787-014-0602-3 Long-term effectiveness of electroconvulsive therapy in adolescents with schizophrenia spectrum disorders [Elektronische Daten] [Itziar Flamarique, Inmaculada Baeza, Elena de la Serna, Alexandre Pons, Miguel Bernardo, Josefina Castro-Fornieles] To compare a sample of adolescents with schizophrenia spectrum disorders (SSD) treated with either ECT or antipsychotics (AP) alone at long-term follow-up. Patients diagnosed with SSD (n=21) treated with ECT due to resistance to AP or catatonia under the age of 18years (ECT group), were compared to a randomly selected group of patients with SSD treated only with AP (non-ECT group) (n=21) and matched for age, gender, diagnosis and duration of illness. Baseline data were gathered retrospectively from medical records. Subjects were assessed at follow-up (mean of follow-up period=5.5years; range 2-9years) using several clinical scales such as the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impression Scale (CGI) and the Global Assessment of Functioning (GAF). Improvement in PANSS positive, negative, general, total and CGI and GAF scores between baseline and follow-up assessment did not differ significantly between groups. At follow-up, no differences were observed for the PANSS negative, CGI and GAF scores between groups, but patients in the ECT group still had higher PANSS total, positive and general scores. ECT treatment followed by AP medication in treatment-resistant SSD or catatonia is at least as effective in the long term as AP alone in non-resistant patients. Springer-Verlag Berlin Heidelberg, 2014 Schizophrenia nationallicence Electroconvulsive therapy nationallicence Adolescents nationallicence Psychosis nationallicence Catatonia nationallicence Flamarique Itziar Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut Clinic de Neurociències, Hospital Clínic Universitari de Barcelona, C/Villarroel, 170, 08036, Barcelona, Spain aut Baeza Inmaculada Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut Clinic de Neurociències, Hospital Clínic Universitari de Barcelona, C/Villarroel, 170, 08036, Barcelona, Spain aut de la Serna Elena Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut Clinic de Neurociències, Hospital Clínic Universitari de Barcelona, C/Villarroel, 170, 08036, Barcelona, Spain aut Pons Alexandre Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Barcelona, Spain aut Bernardo Miguel Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Barcelona, Spain aut Castro-Fornieles Josefina Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut Clinic de Neurociències, Hospital Clínic Universitari de Barcelona, C/Villarroel, 170, 08036, Barcelona, Spain aut European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/5(2015-05-01), 517-524 1018-8827 24:5<517 2015 24 787 https://doi.org/10.1007/s00787-014-0602-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00787-014-0602-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Flamarique Itziar Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut Clinic de Neurociències, Hospital Clínic Universitari de Barcelona, C/Villarroel, 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- Baeza Inmaculada Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut Clinic de Neurociències, Hospital Clínic Universitari de Barcelona, C/Villarroel, 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- de la Serna Elena Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut Clinic de Neurociències, Hospital Clínic Universitari de Barcelona, C/Villarroel, 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- Pons Alexandre Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Barcelona, Spain aut NATIONALLICENCE 700 1- Bernardo Miguel Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Barcelona, Spain aut NATIONALLICENCE 700 1- Castro-Fornieles Josefina Department of Child and Adolescent Psychiatry and Psychology, SGR1119, Institut Clinic de Neurociències, Hospital Clínic Universitari de Barcelona, C/Villarroel, 170, 08036, Barcelona, Spain aut NATIONALLICENCE 773 0- European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/5(2015-05-01), 517-524 1018-8827 24:5<517 2015 24 787