caa a22 4500 60547771X CHVBK 20210128100402.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00787-015-0751-z doi (NATIONALLICENCE)springer-10.1007/s00787-015-0751-z ESCAP Expert Article: Borderline personality disorder in adolescence: An expert research review with implications for clinical practice [Elektronische Daten] [Peter Fonagy, Mario Speranza, Patrick Luyten, Michael Kaess, Christel Hessels, Martin Bohus] Borderline personality disorder (BPD) has onset in adolescence, but is typically first diagnosed in young adulthood. This paper provides a narrative review of the current evidence on diagnosis, comorbidity, phenomenology and treatment of BPD in adolescence. Instruments available for diagnosis are reviewed and their strengths and limitations discussed. Having confirmed the robustness of the diagnosis and the potential for its reliable clinical assessment, we then explore current understandings of the mechanisms of the disorder and focus on neurobiological underpinnings and research on psychological mechanisms. Findings are accumulating to suggest that adolescent BPD has an underpinning biology that is similar in some ways to adult BPD but differs in some critical features. Evidence for interventions focuses on psychological therapies. Several encouraging research studies suggest that early effective treatment is possible. Treatment development has just begun, and while adolescent-specific interventions are still in the process of evolution, most existing therapies represent adaptations of adult models to this developmental phase. There is also a significant opportunity for prevention, albeit there are few data to date to support such initiatives. This review emphasizes that there can be no justification for failing to make an early diagnosis of this enduring and pervasive problem. Springer-Verlag Berlin Heidelberg, 2015 Borderline personality disorder nationallicence Adolescence nationallicence Neurobiology nationallicence Psychotherapy nationallicence Pharmacotherapy nationallicence Fonagy Peter Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, WC1E 6BT, London, UK aut Speranza Mario Department of Child and Adolescent Psychiatry, Versailles General Hospital, Faculty of Health Sciences, Research Unit EA4047, University of Versailles Saint-Quentin-en-Yvelines, 177 rue de Versailles, 78157, Le Chesnay, France aut Luyten Patrick Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, WC1E 6BT, London, UK aut Kaess Michael Department of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Blumenstrasse 8, 69115, Heidelberg, Germany aut Hessels Christel Expertise Centre for Personality Disorders, GGz Centraal, PO Box 3051, 3800 DB, Amersfoort, The Netherlands aut Bohus Martin Department of Psychosomatics and Psychotherapy, Central Institute of Mental Health Mannheim, Heidelberg University, J5, 68159, Mannheim, Germany aut European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/11(2015-11-01), 1307-1320 1018-8827 24:11<1307 2015 24 787 https://doi.org/10.1007/s00787-015-0751-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00787-015-0751-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fonagy Peter Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, WC1E 6BT, London, UK aut NATIONALLICENCE 700 1- Speranza Mario Department of Child and Adolescent Psychiatry, Versailles General Hospital, Faculty of Health Sciences, Research Unit EA4047, University of Versailles Saint-Quentin-en-Yvelines, 177 rue de Versailles, 78157, Le Chesnay, France aut NATIONALLICENCE 700 1- Luyten Patrick Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, WC1E 6BT, London, UK aut NATIONALLICENCE 700 1- Kaess Michael Department of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Blumenstrasse 8, 69115, Heidelberg, Germany aut NATIONALLICENCE 700 1- Hessels Christel Expertise Centre for Personality Disorders, GGz Centraal, PO Box 3051, 3800 DB, Amersfoort, The Netherlands aut NATIONALLICENCE 700 1- Bohus Martin Department of Psychosomatics and Psychotherapy, Central Institute of Mental Health Mannheim, Heidelberg University, J5, 68159, Mannheim, Germany aut NATIONALLICENCE 773 0- European Child & Adolescent Psychiatry Springer Berlin Heidelberg 24/11(2015-11-01), 1307-1320 1018-8827 24:11<1307 2015 24 787