caa a22 4500 60547866X CHVBK 20210128100406.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s10741-014-9434-y doi (NATIONALLICENCE)springer-10.1007/s10741-014-9434-y Guglin Maya Mechanical Assisted Circulation Program, University of Kentucky, Lexington, KY, USA aut How to increase the utilization of donor hearts? [Elektronische Daten] [Maya Guglin] Cardiac transplantation is the best treatment available for patients with end-stage cardiomyopathy. Shortage of donor hearts is the main factor limiting the use of this treatment. Many donor hearts are rejected for transplantation because of left ventricular (LV) systolic dysfunction and/or wall motion abnormalities. While some donors have true cardiomyopathy, a significant proportion has reversible LV dysfunction due to neurogenic stunned myocardium. This condition is triggered by excess of catecholamines, which is typical for brain-dead donors. If given time to recover, LV function may improve, and the heart will be suitable for transplantation. Moreover, limiting of exogenous catecholamines may facilitate the recovery. In this review, we summarize the data on LV dysfunction/wall motion abnormalities in heart donors and propose the strategy to increase the utilization of donor hearts. Springer Science+Business Media New York, 2014 Heart failure nationallicence Heart transplantation nationallicence Neurogenic stunned myocardium nationallicence Takotsubo cardiomyopathy nationallicence Heart Failure Reviews Springer US; http://www.springer-ny.com 20/1(2015-01-01), 95-105 1382-4147 20:1<95 2015 20 10741 https://doi.org/10.1007/s10741-014-9434-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10741-014-9434-y text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Guglin Maya Mechanical Assisted Circulation Program, University of Kentucky, Lexington, KY, USA aut NATIONALLICENCE 773 0- Heart Failure Reviews Springer US; http://www.springer-ny.com 20/1(2015-01-01), 95-105 1382-4147 20:1<95 2015 20 10741