Chemotherapy-induced cardiomyopathy

Verfasser / Beitragende:
[Angela Higgins, Thomas O'Halloran, James Chang]
Ort, Verlag, Jahr:
2015
Enthalten in:
Heart Failure Reviews, 20/6(2015-11-01), 721-730
Format:
Artikel (online)
ID: 605478767
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024 7 0 |a 10.1007/s10741-015-9502-y  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10741-015-9502-y 
245 0 0 |a Chemotherapy-induced cardiomyopathy  |h [Elektronische Daten]  |c [Angela Higgins, Thomas O'Halloran, James Chang] 
520 3 |a Cardiomyopathy is an adverse outcome of antineoplastic drug therapy that has become increasingly relevant in the management of cancer survivors. As the efficacy of anticancer treatments has improved, long-term outcomes are altered by the development of cardiotoxicity, which may be associated with an even worse prognosis than that of the underlying malignancy. From the research into mechanisms, prevention, and treatment, the specialized field of cardio-oncology has evolved, but the recognition and appropriate management of these patients is important for the general internist and general cardiologist as well. Although antineoplastic chemotherapy can cause multiple forms of cardiotoxicity, including arrhythmia, pericardial disease, valvular dysfunction, and myocardial ischemia, in this review we will focus on chemotherapeutic agents associated with cardiomyopathies, from the anthracyclines to newer, the so-called targeted agents such as tyrosine kinase inhibitors. We also review the diagnostic modalities for chemotherapy-induced cardiomyopathy as well as the prevention and treatment strategies which may prolong the lives of those suffering from cancer. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Chemotherapy  |2 nationallicence 
690 7 |a Cardiomyopathy  |2 nationallicence 
690 7 |a Heart failure  |2 nationallicence 
690 7 |a Cancer  |2 nationallicence 
690 7 |a Cardio-oncology  |2 nationallicence 
700 1 |a Higgins  |D Angela  |u Department of Medicine, Beth Israel Deaconess Medical Center, Deaconess Building, Suite 306, One Deaconess Road, 02215, Boston, MA, USA  |4 aut 
700 1 |a O'Halloran  |D Thomas  |u Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA  |4 aut 
700 1 |a Chang  |D James  |u Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA  |4 aut 
773 0 |t Heart Failure Reviews  |d Springer US; http://www.springer-ny.com  |g 20/6(2015-11-01), 721-730  |x 1382-4147  |q 20:6<721  |1 2015  |2 20  |o 10741 
856 4 0 |u https://doi.org/10.1007/s10741-015-9502-y  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Higgins  |D Angela  |u Department of Medicine, Beth Israel Deaconess Medical Center, Deaconess Building, Suite 306, One Deaconess Road, 02215, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a O'Halloran  |D Thomas  |u Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chang  |D James  |u Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Heart Failure Reviews  |d Springer US; http://www.springer-ny.com  |g 20/6(2015-11-01), 721-730  |x 1382-4147  |q 20:6<721  |1 2015  |2 20  |o 10741