caa a22 4500 605478899 CHVBK 20210128100407.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1007/s10741-015-9472-0 doi (NATIONALLICENCE)springer-10.1007/s10741-015-9472-0 RV diastolic dysfunction: time to re-evaluate its importance in heart failure [Elektronische Daten] [Richard Axell, Stephen Hoole, James Hampton-Till, Paul White] Right ventricular (RV) diastolic dysfunction was first reported as an indicator for the assessment of ventricular dysfunction in heart failure a little over two decades ago. However, the underlying mechanisms and precise role of RV diastolic dysfunction in heart failure remain poorly described. Complexities in the structure and function of the RV make the detailed assessment of the contractile performance challenging when compared to its left ventricular (LV) counterpart. LV dysfunction is known to directly affect patient outcome in heart failure. As such, the focus has therefore been on LV function. Nevertheless, a strategy for the diagnosis and assessment of RV diastolic dysfunction has not been established. Here, we review the different causal mechanisms underlying RV diastolic dysfunction, summarising the current assessment techniques used in a clinical environment. Finally, we explore the role of load-independent indices of RV contractility, derived from the conductance technique, to fully interrogate the RV and expand our knowledge and understanding of RV diastolic dysfunction. Accurate assessment of RV contractility may yield further important prognostic information that will benefit patients with diastolic heart failure. Springer Science+Business Media New York, 2015 Right ventricle nationallicence Diastolic dysfunction nationallicence Heart failure nationallicence Conductance technique nationallicence Pressure-volume loops nationallicence Axell Richard Medical Physics and Clinical Engineering, Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, CB2 0QQ, Cambridge, UK aut Hoole Stephen Department of Cardiology, Papworth Hospital NHS Foundation Trust, CB23 3RE, Cambridge, UK aut Hampton-Till James Postgraduate Medical Institute, Anglia Ruskin University, Bishop Hall Lane, CM1 1SQ, Chelmsford, Essex, UK aut White Paul Medical Physics and Clinical Engineering, Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, CB2 0QQ, Cambridge, UK aut Heart Failure Reviews Springer US; http://www.springer-ny.com 20/3(2015-05-01), 363-373 1382-4147 20:3<363 2015 20 10741 https://doi.org/10.1007/s10741-015-9472-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10741-015-9472-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Axell Richard Medical Physics and Clinical Engineering, Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, CB2 0QQ, Cambridge, UK aut NATIONALLICENCE 700 1- Hoole Stephen Department of Cardiology, Papworth Hospital NHS Foundation Trust, CB23 3RE, Cambridge, UK aut NATIONALLICENCE 700 1- Hampton-Till James Postgraduate Medical Institute, Anglia Ruskin University, Bishop Hall Lane, CM1 1SQ, Chelmsford, Essex, UK aut NATIONALLICENCE 700 1- White Paul Medical Physics and Clinical Engineering, Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, CB2 0QQ, Cambridge, UK aut NATIONALLICENCE 773 0- Heart Failure Reviews Springer US; http://www.springer-ny.com 20/3(2015-05-01), 363-373 1382-4147 20:3<363 2015 20 10741