caa a22 4500 605478988 CHVBK 20210128100408.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s10741-015-9482-y doi (NATIONALLICENCE)springer-10.1007/s10741-015-9482-y Acid-base and electrolyte abnormalities in heart failure: pathophysiology and implications [Elektronische Daten] [Caterina Urso, Salvatore Brucculeri, Gregorio Caimi] Electrolyte and acid-base abnormalities are a frequent and potentially dangerous complication in subjects with congestive heart failure. This may be due either to the pathophysiological alterations present in the heart failure state leading to neurohumoral activation (stimulation of the renin-angiotensin-aldosterone system, sympathoadrenergic stimulation), or to the adverse events of therapy with diuretics, cardiac glycosides, and ACE inhibitors. Subjects with heart failure may show hyponatremia, magnesium, and potassium deficiencies; the latter two play a pivotal role in the development of cardiac arrhythmias. The early identification of these alterations and the knowledge of the pathophysiological mechanisms are very useful for the management of these patients. The Author(s), 2015 Acid-base disturbances nationallicence Congestive heart failure nationallicence Electrolyte abnormalities nationallicence Urso Caterina Dipartimento Biomedico di Medicina Interna e Specialistica, Universitá di Palermo, 90127, Palermo, Italy aut Brucculeri Salvatore Dipartimento Biomedico di Medicina Interna e Specialistica, Universitá di Palermo, 90127, Palermo, Italy aut Caimi Gregorio Dipartimento Biomedico di Medicina Interna e Specialistica, Universitá di Palermo, 90127, Palermo, Italy aut Heart Failure Reviews Springer US; http://www.springer-ny.com 20/4(2015-07-01), 493-503 1382-4147 20:4<493 2015 20 10741 https://doi.org/10.1007/s10741-015-9482-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10741-015-9482-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Urso Caterina Dipartimento Biomedico di Medicina Interna e Specialistica, Universitá di Palermo, 90127, Palermo, Italy aut NATIONALLICENCE 700 1- Brucculeri Salvatore Dipartimento Biomedico di Medicina Interna e Specialistica, Universitá di Palermo, 90127, Palermo, Italy aut NATIONALLICENCE 700 1- Caimi Gregorio Dipartimento Biomedico di Medicina Interna e Specialistica, Universitá di Palermo, 90127, Palermo, Italy aut NATIONALLICENCE 773 0- Heart Failure Reviews Springer US; http://www.springer-ny.com 20/4(2015-07-01), 493-503 1382-4147 20:4<493 2015 20 10741