caa a22 4500 605479186 CHVBK 20210128100409.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s10741-014-9463-6 doi (NATIONALLICENCE)springer-10.1007/s10741-014-9463-6 Nuclear imaging for cardiac amyloidosis [Elektronische Daten] [Walter Noordzij, Andor Glaudemans, Simone Longhi, Riemer Slart, Massimiliano Lorenzini, Bouke Hazenberg, Claudio Rapezzi] Histological analysis of endomyocardial tissue is still the gold standard for the diagnosis of cardiac amyloidosis, but has its limitations. Accordingly, there is a need for non-invasive modalities to diagnose cardiac amyloidosis. Echocardiography and ultrasound and magnetic resonance imaging can show characteristics which may not be very specific for cardiac amyloid. Nuclear medicine has gained a precise role in this context: several imaging modalities have become available for the diagnosis and prognostic stratification of cardiac amyloidosis during the last two decades. The different classes of radiopharmaceuticals have the potential to bind different constituents of the amyloidotic infiltrates, with some relevant differences among the various aetiologic types of amyloidosis and the different organs and tissues involved. This review focuses on the background of the commonly used modalities, their present clinical applications, and future clinical perspectives in imaging patients with (suspected) cardiac amyloidosis. The main focus is on conventional nuclear medicine (bone scintigraphy, cardiac sympathetic innervation) and positron emission tomography. Springer Science+Business Media New York, 2014 Amyloidosis nationallicence Nuclear medicine nationallicence PET nationallicence MIBG nationallicence Bone scintigraphy nationallicence Noordzij Walter Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands aut Glaudemans Andor Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands aut Longhi Simone Department of Cardiology, University of Bologna, Bologna, Italy aut Slart Riemer Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands aut Lorenzini Massimiliano Department of Cardiology, University of Bologna, Bologna, Italy aut Hazenberg Bouke Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands aut Rapezzi Claudio Department of Cardiology, University of Bologna, Bologna, Italy aut Heart Failure Reviews Springer US; http://www.springer-ny.com 20/2(2015-03-01), 145-154 1382-4147 20:2<145 2015 20 10741 https://doi.org/10.1007/s10741-014-9463-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10741-014-9463-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Noordzij Walter Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands aut NATIONALLICENCE 700 1- Glaudemans Andor Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands aut NATIONALLICENCE 700 1- Longhi Simone Department of Cardiology, University of Bologna, Bologna, Italy aut NATIONALLICENCE 700 1- Slart Riemer Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands aut NATIONALLICENCE 700 1- Lorenzini Massimiliano Department of Cardiology, University of Bologna, Bologna, Italy aut NATIONALLICENCE 700 1- Hazenberg Bouke Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands aut NATIONALLICENCE 700 1- Rapezzi Claudio Department of Cardiology, University of Bologna, Bologna, Italy aut NATIONALLICENCE 773 0- Heart Failure Reviews Springer US; http://www.springer-ny.com 20/2(2015-03-01), 145-154 1382-4147 20:2<145 2015 20 10741