Sub-population analysis of deformability distribution in heterogeneous red blood cell population
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| 005 | 20210128100410.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20151201xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s10544-015-0007-1 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10544-015-0007-1 | ||
| 245 | 0 | 0 | |a Sub-population analysis of deformability distribution in heterogeneous red blood cell population |h [Elektronische Daten] |c [Dong Lee, Il Doh, Frans Kuypers, Young-Ho Cho] |
| 520 | 3 | |a We present a method for sub-population analysis of deformability distribution using single-cell microchamber array (SiCMA) technology. It is a unique method allowing the correlation of overall cellular characteristics with surface and cytosolic characteristics to define the distribution of individual cellular characteristics in heterogeneous cell populations. As a proof of principle, reticulocytes, the immature sub-population of red blood cells (RBC), were recognized from RBC population by a surface marker and different characteristics on deformability between these populations were characterized. The proposed technology can be used in a variety of applications that would benefit from the ability to measure the distribution of cellular characteristics in complex populations, especially important to define hematologic disorders. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Single cell analysis |2 nationallicence | |
| 690 | 7 | |a Deformability distribution |2 nationallicence | |
| 690 | 7 | |a Sub-population analysis |2 nationallicence | |
| 690 | 7 | |a Microchamber array |2 nationallicence | |
| 700 | 1 | |a Lee |D Dong |u Central R&D Institute, Samsung Electro-mechanics Co., Ltd., Suwon, Republic of Korea |4 aut | |
| 700 | 1 | |a Doh |D Il |u Center for Medical Metrology, Korea Research Institute of Standards and Science (KRISS), Daejeon, Republic of Korea |4 aut | |
| 700 | 1 | |a Kuypers |D Frans |u Department of Hematology, Children's Hospital Oakland Research Institute, Oakland, CA, USA |4 aut | |
| 700 | 1 | |a Cho |D Young-Ho |u Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea |4 aut | |
| 773 | 0 | |t Biomedical Microdevices |d Springer US; http://www.springer-ny.com |g 17/6(2015-12-01), 1-5 |x 1387-2176 |q 17:6<1 |1 2015 |2 17 |o 10544 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10544-015-0007-1 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10544-015-0007-1 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lee |D Dong |u Central R&D Institute, Samsung Electro-mechanics Co., Ltd., Suwon, Republic of Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Doh |D Il |u Center for Medical Metrology, Korea Research Institute of Standards and Science (KRISS), Daejeon, Republic of Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuypers |D Frans |u Department of Hematology, Children's Hospital Oakland Research Institute, Oakland, CA, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cho |D Young-Ho |u Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Biomedical Microdevices |d Springer US; http://www.springer-ny.com |g 17/6(2015-12-01), 1-5 |x 1387-2176 |q 17:6<1 |1 2015 |2 17 |o 10544 | ||