Electrical sensing of DNA-hybridization using two-port network based on suspended carbon nanotube membrane

Verfasser / Beitragende:
[Tun Wang, Ze-Zhi Zheng, Xing-Xing Feng, Hong Chen, Miao Lu]
Ort, Verlag, Jahr:
2015
Enthalten in:
Biomedical Microdevices, 17/6(2015-12-01), 1-7
Format:
Artikel (online)
ID: 605479623
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024 7 0 |a 10.1007/s10544-015-0009-z  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10544-015-0009-z 
245 0 0 |a Electrical sensing of DNA-hybridization using two-port network based on suspended carbon nanotube membrane  |h [Elektronische Daten]  |c [Tun Wang, Ze-Zhi Zheng, Xing-Xing Feng, Hong Chen, Miao Lu] 
520 3 |a An approach was presented for electrical sensing of deoxyribonucleic acid (DNA)-hybridization in solution using a two-port network based on single-walled suspended carbon nanotube (SWCNT) membrane. A single stranded probe DNA (5′-NH2-(CH2)6-CGC CGA TTG GAC AAA ACT TAA A-3′) was immobilized on the SWCNT membrane. A solution with the complementary single stranded DNA (D′FITC: 5′-FITC-T TTA AGT TTT GTC CAA TCG GCG-3′) in various concentrations was then dropped on the membrane. The two-port network composed of the suspended SWCNT membrane and its underneath gate were characterized by coupling with a vector network analyzer. The resonance frequency of transmission coefficient S21 was observed to be around 10MHz. The resonance frequency shifts with DNA-hybridization, and the sensing limit was approximately 50 nM. The advantages of this approach include low-noise frequency output, solution based real time detection and capable of on-chip integration, etc. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a DNA detection  |2 nationallicence 
690 7 |a Suspended carbon nanotube membrane  |2 nationallicence 
690 7 |a Two-port network  |2 nationallicence 
700 1 |a Wang  |D Tun  |u Pen-Tung Sah Institute of Micro-Nano Science & Technology, Xiamen University, 361005, Xiamen, People's Republic of China  |4 aut 
700 1 |a Zheng  |D Ze-Zhi  |u Department of Physics, Xiamen University, 361005, Xiamen, China  |4 aut 
700 1 |a Feng  |D Xing-Xing  |u Pen-Tung Sah Institute of Micro-Nano Science & Technology, Xiamen University, 361005, Xiamen, People's Republic of China  |4 aut 
700 1 |a Chen  |D Hong  |u Pen-Tung Sah Institute of Micro-Nano Science & Technology, Xiamen University, 361005, Xiamen, People's Republic of China  |4 aut 
700 1 |a Lu  |D Miao  |u Pen-Tung Sah Institute of Micro-Nano Science & Technology, Xiamen University, 361005, Xiamen, People's Republic of China  |4 aut 
773 0 |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/6(2015-12-01), 1-7  |x 1387-2176  |q 17:6<1  |1 2015  |2 17  |o 10544 
856 4 0 |u https://doi.org/10.1007/s10544-015-0009-z  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10544-015-0009-z  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wang  |D Tun  |u Pen-Tung Sah Institute of Micro-Nano Science & Technology, Xiamen University, 361005, Xiamen, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zheng  |D Ze-Zhi  |u Department of Physics, Xiamen University, 361005, Xiamen, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Feng  |D Xing-Xing  |u Pen-Tung Sah Institute of Micro-Nano Science & Technology, Xiamen University, 361005, Xiamen, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chen  |D Hong  |u Pen-Tung Sah Institute of Micro-Nano Science & Technology, Xiamen University, 361005, Xiamen, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lu  |D Miao  |u Pen-Tung Sah Institute of Micro-Nano Science & Technology, Xiamen University, 361005, Xiamen, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/6(2015-12-01), 1-7  |x 1387-2176  |q 17:6<1  |1 2015  |2 17  |o 10544