Microtubule guiding in a multi-walled carbon nanotube circuit
Gespeichert in:
Verfasser / Beitragende:
[Aurélien Sikora, Javier Ramón-Azcón, Mustafa Sen, Kyongwan Kim, Hikaru Nakazawa, Mitsuo Umetsu, Izumi Kumagai, Hitoshi Shiku, Tomokazu Matsue, Winfried Teizer]
Ort, Verlag, Jahr:
2015
Enthalten in:
Biomedical Microdevices, 17/4(2015-08-01), 1-6
Format:
Artikel (online)
Online Zugang:
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| 024 | 7 | 0 | |a 10.1007/s10544-015-9978-1 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10544-015-9978-1 | ||
| 245 | 0 | 0 | |a Microtubule guiding in a multi-walled carbon nanotube circuit |h [Elektronische Daten] |c [Aurélien Sikora, Javier Ramón-Azcón, Mustafa Sen, Kyongwan Kim, Hikaru Nakazawa, Mitsuo Umetsu, Izumi Kumagai, Hitoshi Shiku, Tomokazu Matsue, Winfried Teizer] |
| 520 | 3 | |a In nanotechnological devices, mass transport can be initiated by pressure driven flow, diffusion or by employing molecular motors. As the scale decreases, molecular motors can be helpful as they are not limited by increased viscous resistance. Moreover, molecular motors can move against diffusion gradients and are naturally fitted for nanoscale transportation. Among motor proteins, kinesin has particular potential for lab-on-a-chip applications. It can be used for sorting, concentrating or as a mechanical sensor. When bound to a surface, kinesin motors propel microtubules in random directions, depending on their landing orientation. In order to circumvent this complication, the microtubule motion should be confined or guided. To this end, dielectrophoretically aligned multi-walled-carbon nanotubes (MWCNT) can be employed as nanotracks. In order to control more precisely the spatial repartition of the MWCNTs, a screening method has been implemented and tested. Polygonal patterns have been fabricated with the aim of studying the guiding and the microtubule displacement between MWCNT segments. Microtubules are observed to transfer between MWCNT segments, a prerequisite for the guiding of microtubules in MWCNT circuit-based biodevices. The effect of the MWCNT organization (crenellated or hexagonal) on the MT travel distance has been investigated as well. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Carbon |2 nationallicence | |
| 690 | 7 | |a Nanotube |2 nationallicence | |
| 690 | 7 | |a Microtubule |2 nationallicence | |
| 690 | 7 | |a Kinesin |2 nationallicence | |
| 690 | 7 | |a Dielectrophoresis |2 nationallicence | |
| 700 | 1 | |a Sikora |D Aurélien |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | |
| 700 | 1 | |a Ramón-Azcón |D Javier |u Department of Chemical and Biomolecular Nanotechnology, Advanced Chemical Research Institute of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain |4 aut | |
| 700 | 1 | |a Sen |D Mustafa |u Graduate School of Environmental Studies, Tohoku University, 980-8579, Sendai, Japan |4 aut | |
| 700 | 1 | |a Kim |D Kyongwan |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | |
| 700 | 1 | |a Nakazawa |D Hikaru |u Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, 980-8579, Sendai, Japan |4 aut | |
| 700 | 1 | |a Umetsu |D Mitsuo |u Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, 980-8579, Sendai, Japan |4 aut | |
| 700 | 1 | |a Kumagai |D Izumi |u Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, 980-8579, Sendai, Japan |4 aut | |
| 700 | 1 | |a Shiku |D Hitoshi |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | |
| 700 | 1 | |a Matsue |D Tomokazu |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | |
| 700 | 1 | |a Teizer |D Winfried |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | |
| 773 | 0 | |t Biomedical Microdevices |d Springer US; http://www.springer-ny.com |g 17/4(2015-08-01), 1-6 |x 1387-2176 |q 17:4<1 |1 2015 |2 17 |o 10544 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10544-015-9978-1 |q text/html |z Onlinezugriff via DOI |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sikora |D Aurélien |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ramón-Azcón |D Javier |u Department of Chemical and Biomolecular Nanotechnology, Advanced Chemical Research Institute of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sen |D Mustafa |u Graduate School of Environmental Studies, Tohoku University, 980-8579, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kim |D Kyongwan |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nakazawa |D Hikaru |u Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, 980-8579, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Umetsu |D Mitsuo |u Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, 980-8579, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kumagai |D Izumi |u Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, 980-8579, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shiku |D Hitoshi |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Matsue |D Tomokazu |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Teizer |D Winfried |u WPI Advanced Institute for Materials Research, Tohoku University, 2-1-1 Katahira, 980-8577, Sendai, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Biomedical Microdevices |d Springer US; http://www.springer-ny.com |g 17/4(2015-08-01), 1-6 |x 1387-2176 |q 17:4<1 |1 2015 |2 17 |o 10544 | ||