Early prognosis of metastasis risk in inflammatory breast cancer by texture analysis of tumour microscopic images
| LEADER | caa a22 4500 | ||
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| 001 | 605480095 | ||
| 003 | CHVBK | ||
| 005 | 20210128100413.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20151001xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s10544-015-9999-9 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10544-015-9999-9 | ||
| 245 | 0 | 0 | |a Early prognosis of metastasis risk in inflammatory breast cancer by texture analysis of tumour microscopic images |h [Elektronische Daten] |c [Daniela Kolarevic, Zorica Tomasevic, Radan Dzodic, Ksenija Kanjer, Dragica Vukosavljevic, Marko Radulovic] |
| 520 | 3 | |a Inflammatory breast cancer (IBC) is a rare and aggressive type of locally advanced breast cancer. The purpose of this study was to determine the value of microscopic tumour histomorphology texture for prognosis of local and systemic recurrence at the time of initial IBC diagnosis. This retrospective study included a group of 52 patients selected on the basis of non-metastatic IBC diagnosis, stage IIIB. Gray-Level-Co-Occurrence-Matrix (GLCM) texture analysis was performed on digital images of primary tumour tissue sections stained with haematoxylin/eosin. Obtained values were categorized by use of both data- and outcome-based methods. All five acquired GLCM texture features significantly associated with metastasis outcome. By accuracies of 69-81% and AUCs of 0.71-0.81, prognostic performance of GLCM parameters exceeded that of standard major IBC clinical prognosticators such as tumour grade and response to induction chemotherapy. Furthermore, a composite score consisting of tumour grade, contrast and correlation as independent features resulted in further enhancement of prognostic performance by accuracy of 89%, discrimination efficiency by AUC of 0.93 and an outstanding hazard ratio of 71.6 (95%CI, 41.7-148.4). Internal validation was successfully performed by bootstrap and split-sample cross-validation, suggesting that the model is generalizable. This study indicates for the first time the potential use of primary breast tumour histology texture as a highly accurate, simple and cost-effective prognostic indicator of metastasis risk in IBC. Clinical relevance of the obtained results rests on the role of prognosis in decisions on induction chemotherapy and the resulting impact on quality of life and survival. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Inflammatory breast cancer |2 nationallicence | |
| 690 | 7 | |a Image analysis |2 nationallicence | |
| 690 | 7 | |a Prognosis |2 nationallicence | |
| 690 | 7 | |a Prognostic factor |2 nationallicence | |
| 690 | 7 | |a Metastasis |2 nationallicence | |
| 690 | 7 | |a Histology texture |2 nationallicence | |
| 690 | 7 | |a GLCM |2 nationallicence | |
| 700 | 1 | |a Kolarevic |D Daniela |u Daily Chemotherapy Hospital, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Tomasevic |D Zorica |u Daily Chemotherapy Hospital, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Dzodic |D Radan |u Surgical Oncology Clinic, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Kanjer |D Ksenija |u Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Vukosavljevic |D Dragica |u Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Radulovic |D Marko |u Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia |4 aut | |
| 773 | 0 | |t Biomedical Microdevices |d Springer US; http://www.springer-ny.com |g 17/5(2015-10-01), 1-8 |x 1387-2176 |q 17:5<1 |1 2015 |2 17 |o 10544 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10544-015-9999-9 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10544-015-9999-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kolarevic |D Daniela |u Daily Chemotherapy Hospital, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tomasevic |D Zorica |u Daily Chemotherapy Hospital, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Dzodic |D Radan |u Surgical Oncology Clinic, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kanjer |D Ksenija |u Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vukosavljevic |D Dragica |u Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Radulovic |D Marko |u Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 14, 11000, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Biomedical Microdevices |d Springer US; http://www.springer-ny.com |g 17/5(2015-10-01), 1-8 |x 1387-2176 |q 17:5<1 |1 2015 |2 17 |o 10544 | ||