Fabrication and evaluation of an improved polymer-based cochlear electrode array for atraumatic insertion
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| 024 | 7 | 0 | |a 10.1007/s10544-015-9941-1 |2 doi |
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| 245 | 0 | 0 | |a Fabrication and evaluation of an improved polymer-based cochlear electrode array for atraumatic insertion |h [Elektronische Daten] |c [Tae Gwon, Kyou Min, Jin Kim, Seung Oh, Ho Lee, Min-Hyun Park, Sung Kim] |
| 520 | 3 | |a An atraumatic cochlear electrode array has become indispensable to high-performance cochlear implants such as electric acoustic stimulation (EAS), wherein the preservation of residual hearing is significant. For an atraumatic implantation, we propose and demonstrate a new improved design of a cochlear electrode array based on liquid crystal polymer (LCP), which can be fabricated by precise batch processes and a thermal lamination process, in contrast to conventional wire-based cochlear electrode arrays. Using a thin-film process of LCP-film-mounted silicon wafer and thermal press lamination, we devise a multi-layered structure with variable layers of LCP films to achieve a sufficient degree of basal rigidity and a flexible tip. A peripheral blind via and self-aligned silicone elastomer molding process can reduce the width of the array. Measuring the insertion and extraction forces in a human scala tympani model, we investigate five human temporal bone insertion trials and record electrically evoked auditory brainstem responses (EABR) acutely in a guinea pig model. The diameters of the finalized electrode arrays are 0.3mm (tip) and 0.75mm (base). The insertion force with a displacement of 8mm from a round window and the maximum extraction force are 2.4 mN and 34.0 mN, respectively. The electrode arrays can be inserted from 360° to 630° without trauma at the basal turn. The EABR data confirm the efficacy of the array. A new design of LCP-based cochlear electrode array for atraumatic implantation is fabricated. Verification indicates that foretells the development of an atraumatic cochlear electrode array and clinical implant. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Cochlear implantation |2 nationallicence | |
| 690 | 7 | |a Intracochlear electrode array |2 nationallicence | |
| 690 | 7 | |a Liquid crystal polymer |2 nationallicence | |
| 690 | 7 | |a Atraumatic cochlear electrode |2 nationallicence | |
| 690 | 7 | |a Polymer-based neural interface |2 nationallicence | |
| 700 | 1 | |a Gwon |D Tae |u Department of Electrical and Computer Engineering, Seoul National University, Bldg. 301 Room# 1006, Seoul National University, San 56-1, 151-742, Seoul, Shillim-dong, Gwanak-gu, South Korea |4 aut | |
| 700 | 1 | |a Min |D Kyou |u Department of Electrical and Computer Engineering, Seoul National University, Bldg. 301 Room# 1006, Seoul National University, San 56-1, 151-742, Seoul, Shillim-dong, Gwanak-gu, South Korea |4 aut | |
| 700 | 1 | |a Kim |D Jin |u Department of Electrical and Computer Engineering, Seoul National University, Bldg. 301 Room# 1006, Seoul National University, San 56-1, 151-742, Seoul, Shillim-dong, Gwanak-gu, South Korea |4 aut | |
| 700 | 1 | |a Oh |D Seung |u Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, South Korea |4 aut | |
| 700 | 1 | |a Lee |D Ho |u Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, South Korea |4 aut | |
| 700 | 1 | |a Park |D Min-Hyun |u Department of Otorhinolaryngology, Boramae Medical Center, SMG-SNU, Seoul, South Korea |4 aut | |
| 700 | 1 | |a Kim |D Sung |u Department of Electrical and Computer Engineering, Seoul National University, Bldg. 301 Room# 1006, Seoul National University, San 56-1, 151-742, Seoul, Shillim-dong, Gwanak-gu, South Korea |4 aut | |
| 773 | 0 | |t Biomedical Microdevices |d Springer US; http://www.springer-ny.com |g 17/2(2015-04-01), 1-12 |x 1387-2176 |q 17:2<1 |1 2015 |2 17 |o 10544 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10544-015-9941-1 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10544-015-9941-1 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gwon |D Tae |u Department of Electrical and Computer Engineering, Seoul National University, Bldg. 301 Room# 1006, Seoul National University, San 56-1, 151-742, Seoul, Shillim-dong, Gwanak-gu, South Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Min |D Kyou |u Department of Electrical and Computer Engineering, Seoul National University, Bldg. 301 Room# 1006, Seoul National University, San 56-1, 151-742, Seoul, Shillim-dong, Gwanak-gu, South Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kim |D Jin |u Department of Electrical and Computer Engineering, Seoul National University, Bldg. 301 Room# 1006, Seoul National University, San 56-1, 151-742, Seoul, Shillim-dong, Gwanak-gu, South Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Oh |D Seung |u Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, South Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lee |D Ho |u Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, South Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Park |D Min-Hyun |u Department of Otorhinolaryngology, Boramae Medical Center, SMG-SNU, Seoul, South Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kim |D Sung |u Department of Electrical and Computer Engineering, Seoul National University, Bldg. 301 Room# 1006, Seoul National University, San 56-1, 151-742, Seoul, Shillim-dong, Gwanak-gu, South Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Biomedical Microdevices |d Springer US; http://www.springer-ny.com |g 17/2(2015-04-01), 1-12 |x 1387-2176 |q 17:2<1 |1 2015 |2 17 |o 10544 | ||