A three-dimensional electrode for highly efficient electrocoalescence-based droplet merging

Verfasser / Beitragende:
[Adrian Guzman, Hyun Kim, Paul de Figueiredo, Arum Han]
Ort, Verlag, Jahr:
2015
Enthalten in:
Biomedical Microdevices, 17/2(2015-04-01), 1-9
Format:
Artikel (online)
ID: 605480281
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024 7 0 |a 10.1007/s10544-014-9921-x  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10544-014-9921-x 
245 0 2 |a A three-dimensional electrode for highly efficient electrocoalescence-based droplet merging  |h [Elektronische Daten]  |c [Adrian Guzman, Hyun Kim, Paul de Figueiredo, Arum Han] 
520 3 |a Droplet merging is one of the key functions in the ever-widening applications of droplet microfluidics. Enhancing the efficiency of electric field-based droplet merging, namely electrocoalescence, can lead to an increase in platform stability and overcome one of the major bottlenecks in further improving throughputs of droplet microfluidic systems. In this work, a paired three-dimensional (3D) electrode design that can provide a uniform electric field within a droplet merging region, which is also properly aligned with the droplet dipole moments for highly efficient electrocoalescence is presented. A systematic study was conducted to compare the droplet merging performance of the presented 3D electrode design to other commonly used planar electrode, coplanar electrode, dual-coplanar electrode, and liquid metal 3D electrode designs. The presented 3D electrode design reduced the threshold input voltage required to obtain droplet fusion by up to 75%. In addition, a droplet merging efficiency of higher than 95% was consistently observed, compared to less than 85% merging efficiency for the conventionally used electrode designs. We expect that this droplet electrocoalescence design will improve the overall throughput and merging success rate in droplet microfluidic based high-throughput assays. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Droplet microfluidics  |2 nationallicence 
690 7 |a Droplet merging  |2 nationallicence 
690 7 |a Droplet electrocoalescence  |2 nationallicence 
690 7 |a 3D electrode  |2 nationallicence 
700 1 |a Guzman  |D Adrian  |u Department of Electrical and Computer Engineering, Texas A&M University, 77843, College Station, TX, USA  |4 aut 
700 1 |a Kim  |D Hyun  |u Department of Electrical and Computer Engineering, Texas A&M University, 77843, College Station, TX, USA  |4 aut 
700 1 |a de Figueiredo  |D Paul  |u Department of Molecular Pathogenesis and Immunology, Texas A&M Health Science Center, 77807, Bryan, TX, USA  |4 aut 
700 1 |a Han  |D Arum  |u Department of Electrical and Computer Engineering, Texas A&M University, 77843, College Station, TX, USA  |4 aut 
773 0 |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/2(2015-04-01), 1-9  |x 1387-2176  |q 17:2<1  |1 2015  |2 17  |o 10544 
856 4 0 |u https://doi.org/10.1007/s10544-014-9921-x  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10544-014-9921-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Guzman  |D Adrian  |u Department of Electrical and Computer Engineering, Texas A&M University, 77843, College Station, TX, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kim  |D Hyun  |u Department of Electrical and Computer Engineering, Texas A&M University, 77843, College Station, TX, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a de Figueiredo  |D Paul  |u Department of Molecular Pathogenesis and Immunology, Texas A&M Health Science Center, 77807, Bryan, TX, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Han  |D Arum  |u Department of Electrical and Computer Engineering, Texas A&M University, 77843, College Station, TX, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Biomedical Microdevices  |d Springer US; http://www.springer-ny.com  |g 17/2(2015-04-01), 1-9  |x 1387-2176  |q 17:2<1  |1 2015  |2 17  |o 10544