caa a22 4500 605480400 CHVBK 20210128100415.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10544-015-9935-z doi (NATIONALLICENCE)springer-10.1007/s10544-015-9935-z Enhanced sub-micron colloidal particle separation with interdigitated microelectrode arrays using mixed AC/DC dielectrophoretic scheme [Elektronische Daten] [Vikhram Swaminathan, Mark Shannon, Rashid Bashir] Dielectrophoretic separation of particles finds a variety of applications in the capture of species such as cells, viruses, proteins, DNA from biological systems, as well as other organic and inorganic contaminants from water. The ability to capture particles is constrained by poor volumetric scaling of separation force with respect to particle diameter, as well as the weak penetration of electric fields in the media. In order to improve the separation of sub-micron colloids, we present a scheme based on multiple interdigitated electrode arrays under mixed AC/DC bias. The use of high frequency longitudinal AC bias breaks the shielding effects through electroosmotic micromixing to enhance electric fields through the electrolyte, while a transverse DC bias between the electrode arrays enables penetration of the separation force to capture particles from the bulk of the microchannel. We determine the favorable biasing conditions for field enhancement with the help of analytical models, and experimentally demonstrate the improved capture from sub-micron colloidal suspensions with the mixed AC/DC electrostatic excitation scheme over conventional AC-DEP methods. Springer Science+Business Media New York, 2015 Interdigitated electrodes nationallicence Dielectrophoresis nationallicence Colloidal particle nationallicence Particle separation nationallicence Microfluidics nationallicence Swaminathan Vikhram Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 West Green Street, 61801, Urbana, IL, USA aut Shannon Mark Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 West Green Street, 61801, Urbana, IL, USA aut Bashir Rashid Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, 208 North Wright Street, 61801, Urbana, IL, USA aut Biomedical Microdevices Springer US; http://www.springer-ny.com 17/2(2015-04-01), 1-9 1387-2176 17:2<1 2015 17 10544 https://doi.org/10.1007/s10544-015-9935-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10544-015-9935-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Swaminathan Vikhram Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 West Green Street, 61801, Urbana, IL, USA aut NATIONALLICENCE 700 1- Shannon Mark Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 West Green Street, 61801, Urbana, IL, USA aut NATIONALLICENCE 700 1- Bashir Rashid Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, 208 North Wright Street, 61801, Urbana, IL, USA aut NATIONALLICENCE 773 0- Biomedical Microdevices Springer US; http://www.springer-ny.com 17/2(2015-04-01), 1-9 1387-2176 17:2<1 2015 17 10544