Tuning the size of gelatin nanoparticles produced by nanoprecipitation

Verfasser / Beitragende:
[Saeed Khan, Hussain Ali, Ayesha Ihsan, Nadeem Sabir]
Ort, Verlag, Jahr:
2015
Enthalten in:
Colloid Journal, 77/5(2015-09-01), 672-676
Format:
Artikel (online)
ID: 605490015
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024 7 0 |a 10.1134/S1061933X15050105  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1134/S1061933X15050105 
245 0 0 |a Tuning the size of gelatin nanoparticles produced by nanoprecipitation  |h [Elektronische Daten]  |c [Saeed Khan, Hussain Ali, Ayesha Ihsan, Nadeem Sabir] 
520 3 |a The aim of the study was to control the size of gelatin nanoparticles under varied conditions of nanoprecipitation. The gelatin concentration in the solvent phase and different combination of nonsolvents was used to see influence on the size, polydispersity and recovery yield of produced nanoparticles. The size of the nanoparticles was determined by dynamic light scattering. The yield of gelatin nanoparticles after freezedrying was found gravimetrically. The morphology of nanoparticles was studied by scanning electron microscopy. The results suggest that the size of nanoparticles can be tuned within a range 250-350 nm with low polydispersity index because of the inhibition of particle aggregation during crosslinking. The produced nanoparticles are of spherical shape with a smooth surface. We found that the recovery yield was also dependent on the gelatin concentration in the solvent phase. 
540 |a Pleiades Publishing, Ltd., 2015 
700 1 |a Khan  |D Saeed  |u Department of Pharmacy, Kohat University of Science and Technology, 26000, Kohat, Pakistan  |4 aut 
700 1 |a Ali  |D Hussain  |u Department of Pharmacy, Quid-i-Azam University, Islamabad, Pakistan  |4 aut 
700 1 |a Ihsan  |D Ayesha  |u Division of Industrial Biotechnology, NIBGE, Faisalabad, Pakistan  |4 aut 
700 1 |a Sabir  |D Nadeem  |u Department of Physics, Government College University, Faisalabad, Pakistan  |4 aut 
773 0 |t Colloid Journal  |d Pleiades Publishing  |g 77/5(2015-09-01), 672-676  |x 1061-933X  |q 77:5<672  |1 2015  |2 77  |o 10595 
856 4 0 |u https://doi.org/10.1134/S1061933X15050105  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a brief-communication  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1134/S1061933X15050105  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Khan  |D Saeed  |u Department of Pharmacy, Kohat University of Science and Technology, 26000, Kohat, Pakistan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ali  |D Hussain  |u Department of Pharmacy, Quid-i-Azam University, Islamabad, Pakistan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ihsan  |D Ayesha  |u Division of Industrial Biotechnology, NIBGE, Faisalabad, Pakistan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sabir  |D Nadeem  |u Department of Physics, Government College University, Faisalabad, Pakistan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Colloid Journal  |d Pleiades Publishing  |g 77/5(2015-09-01), 672-676  |x 1061-933X  |q 77:5<672  |1 2015  |2 77  |o 10595