Preoperative differentiation between benign and malignant renal masses smaller than 4cm treated with partial nephrectomy

Verfasser / Beitragende:
[Masatomo Nishikawa, Hideaki Miyake, Kazuhiro Kitajima, Satoru Takahashi, Kazuro Sugimura, Masato Fujisawa]
Ort, Verlag, Jahr:
2015
Enthalten in:
International Journal of Clinical Oncology, 20/1(2015-02-01), 150-155
Format:
Artikel (online)
ID: 605490341
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024 7 0 |a 10.1007/s10147-014-0673-7  |2 doi 
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245 0 0 |a Preoperative differentiation between benign and malignant renal masses smaller than 4cm treated with partial nephrectomy  |h [Elektronische Daten]  |c [Masatomo Nishikawa, Hideaki Miyake, Kazuhiro Kitajima, Satoru Takahashi, Kazuro Sugimura, Masato Fujisawa] 
520 3 |a Background: The aim of this study is to accurately differentiate between benign and malignant small renal masses (SRMs) prior to surgery. Methods: The study included 144 patients with SRMs <4cm suspected to be renal cell carcinoma (RCC) based on several imaging examinations, who subsequently underwent partial nephrectomy. Clinicopathological data were analyzed based on the preoperative findings obtained from enhanced computed tomography (CT) as follows: group 1 showing a typical imaging pattern for clear cell RCC (CCRCC), and group 2 showing an imaging pattern atypical of CCRCC. We then evaluated the association between clinicopathological characteristics and pathological diagnosis in order to identify factors which can predict the pathological diagnosis. Results: Based on the criteria, 102 (70.8%) and 42 (29.2%) patients were classified into group 1 and group 2, respectively. The only independent factor identified to predict the final pathological diagnosis of the 144 patients was preoperative CT findings. Only 7 (6.9%) patients were pathologically diagnosed with benign tumors in group 1; however, 13 (31.0%) of the 42 patients in group 2 appeared to have pathologically confirmed benign tumors. A younger age and lower body mass index (BMI) in group 2 were shown to be independently associated with benign histology on multivariate analysis. Conclusions: The proportion of patients with benign tumors was comparatively high in those with CT findings atypical for CCRCC; therefore, other clinical parameters, such as age and BMI, should be considered when determining therapeutic strategies for patients with such SRMs. 
540 |a Japan Society of Clinical Oncology, 2014 
690 7 |a Small renal mass  |2 nationallicence 
690 7 |a Enhanced computed tomography  |2 nationallicence 
690 7 |a Age  |2 nationallicence 
690 7 |a Body mass index  |2 nationallicence 
700 1 |a Nishikawa  |D Masatomo  |u Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan  |4 aut 
700 1 |a Miyake  |D Hideaki  |u Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan  |4 aut 
700 1 |a Kitajima  |D Kazuhiro  |u Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan  |4 aut 
700 1 |a Takahashi  |D Satoru  |u Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan  |4 aut 
700 1 |a Sugimura  |D Kazuro  |u Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan  |4 aut 
700 1 |a Fujisawa  |D Masato  |u Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan  |4 aut 
773 0 |t International Journal of Clinical Oncology  |d Springer Japan  |g 20/1(2015-02-01), 150-155  |x 1341-9625  |q 20:1<150  |1 2015  |2 20  |o 10147 
856 4 0 |u https://doi.org/10.1007/s10147-014-0673-7  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10147-014-0673-7  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nishikawa  |D Masatomo  |u Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Miyake  |D Hideaki  |u Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kitajima  |D Kazuhiro  |u Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Takahashi  |D Satoru  |u Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sugimura  |D Kazuro  |u Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fujisawa  |D Masato  |u Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t International Journal of Clinical Oncology  |d Springer Japan  |g 20/1(2015-02-01), 150-155  |x 1341-9625  |q 20:1<150  |1 2015  |2 20  |o 10147