caa a22 4500 605490341 CHVBK 20210128100504.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10147-014-0673-7 doi (NATIONALLICENCE)springer-10.1007/s10147-014-0673-7 Preoperative differentiation between benign and malignant renal masses smaller than 4cm treated with partial nephrectomy [Elektronische Daten] [Masatomo Nishikawa, Hideaki Miyake, Kazuhiro Kitajima, Satoru Takahashi, Kazuro Sugimura, Masato Fujisawa] Background: The aim of this study is to accurately differentiate between benign and malignant small renal masses (SRMs) prior to surgery. Methods: The study included 144 patients with SRMs <4cm suspected to be renal cell carcinoma (RCC) based on several imaging examinations, who subsequently underwent partial nephrectomy. Clinicopathological data were analyzed based on the preoperative findings obtained from enhanced computed tomography (CT) as follows: group 1 showing a typical imaging pattern for clear cell RCC (CCRCC), and group 2 showing an imaging pattern atypical of CCRCC. We then evaluated the association between clinicopathological characteristics and pathological diagnosis in order to identify factors which can predict the pathological diagnosis. Results: Based on the criteria, 102 (70.8%) and 42 (29.2%) patients were classified into group 1 and group 2, respectively. The only independent factor identified to predict the final pathological diagnosis of the 144 patients was preoperative CT findings. Only 7 (6.9%) patients were pathologically diagnosed with benign tumors in group 1; however, 13 (31.0%) of the 42 patients in group 2 appeared to have pathologically confirmed benign tumors. A younger age and lower body mass index (BMI) in group 2 were shown to be independently associated with benign histology on multivariate analysis. Conclusions: The proportion of patients with benign tumors was comparatively high in those with CT findings atypical for CCRCC; therefore, other clinical parameters, such as age and BMI, should be considered when determining therapeutic strategies for patients with such SRMs. Japan Society of Clinical Oncology, 2014 Small renal mass nationallicence Enhanced computed tomography nationallicence Age nationallicence Body mass index nationallicence Nishikawa Masatomo Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan aut Miyake Hideaki Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan aut Kitajima Kazuhiro Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan aut Takahashi Satoru Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan aut Sugimura Kazuro Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan aut Fujisawa Masato Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan aut International Journal of Clinical Oncology Springer Japan 20/1(2015-02-01), 150-155 1341-9625 20:1<150 2015 20 10147 https://doi.org/10.1007/s10147-014-0673-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10147-014-0673-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nishikawa Masatomo Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan aut NATIONALLICENCE 700 1- Miyake Hideaki Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan aut NATIONALLICENCE 700 1- Kitajima Kazuhiro Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan aut NATIONALLICENCE 700 1- Takahashi Satoru Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan aut NATIONALLICENCE 700 1- Sugimura Kazuro Division of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan aut NATIONALLICENCE 700 1- Fujisawa Masato Division of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Japan aut NATIONALLICENCE 773 0- International Journal of Clinical Oncology Springer Japan 20/1(2015-02-01), 150-155 1341-9625 20:1<150 2015 20 10147