caa a22 4500 60549083X CHVBK 20210128100506.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10147-014-0723-1 doi (NATIONALLICENCE)springer-10.1007/s10147-014-0723-1 Effect on HPV vaccination in Japan resulting from news report of adverse events and suspension of governmental recommendation for HPV vaccination [Elektronische Daten] [Akiko Morimoto, Yutaka Ueda, Tomomi Egawa-Takata, Asami Yagi, Yoshito Terai, Masahide Ohmichi, Tomoyuki Ichimura, Toshiyuki Sumi, Hiromi Murata, Hideharu Kanzaki, Hidekatsu Nakai, Masaki Mandai, Kiyoshi Yoshino, Masami Fujita, Tadashi Kimura, Junko Saito, Tomotaka Sobue, Nobumichi Nishikawa, Masayuki Sekine, Takayuki Enomoto, Yorihiko Horikoshi, Tetsu Takagi] Background: Administration of the human papillomavirus (HPV) vaccine decreased dramatically in Japan after extensive news of adverse vaccine events and suspension of the governmental recommendation for the vaccine. In this study, we investigated the knowledge and acceptance of vaccinated adolescents concerning cervical cancer, cancer screening and the HPV vaccine. Furthermore, we analyzed whether and by how much the news affected acceptance of the vaccination. Methods: This study was conducted as a part of Osaka Clinical resEArch of HPV vacciNe (OCEAN) study. A questionnaire was distributed to 2,777 study registrants. Results: The response rate was 38%. The recognition rate of the news of the vaccine's adverse events was 80%; it was 68% for awareness of the government's announcement of the suspension of its recommendation for the vaccine. Among those who had a chance to hear or see the negative news during their vaccination period, 46 (60%) continued vaccination while knowing of the news, 22 (29%) discontinued vaccination, and 9 (11%) continued vaccination without an awareness of the news. Reports of the vaccine's adverse events were the main reason for not continuing the vaccination series. Those who consulted doctors after hearing the adverse news were significantly more likely to continue their vaccinations than those who did not. Conclusions: Our results should help in understanding the need for a strong promotion of vaccine usage and cancer screening after future retraction of the recommendation suspension. This may apply to other countries with an unsatisfactory rate of HPV vaccination due to fears of adverse vaccine events. Japan Society of Clinical Oncology, 2014 HPV vaccine nationallicence Adverse events nationallicence Media reports nationallicence Governmental suspension of vaccination nationallicence Japan nationallicence Morimoto Akiko The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Ueda Yutaka The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Egawa-Takata Tomomi The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Yagi Asami Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, 565-0871, Suita, Osaka, Japan aut Terai Yoshito The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Ohmichi Masahide The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Ichimura Tomoyuki The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Sumi Toshiyuki The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Murata Hiromi The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Kanzaki Hideharu The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Nakai Hidekatsu The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Mandai Masaki The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Yoshino Kiyoshi The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Fujita Masami The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Kimura Tadashi The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Saito Junko The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Sobue Tomotaka Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, 565-0871, Suita, Osaka, Japan aut Nishikawa Nobumichi Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, 951-8510, Chuo-ku, Niigata, Japan aut Sekine Masayuki Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, 951-8510, Chuo-ku, Niigata, Japan aut Enomoto Takayuki The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Horikoshi Yorihiko The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut Takagi Tetsu The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut International Journal of Clinical Oncology Springer Japan 20/3(2015-06-01), 549-555 1341-9625 20:3<549 2015 20 10147 https://doi.org/10.1007/s10147-014-0723-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10147-014-0723-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Morimoto Akiko The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Ueda Yutaka The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Egawa-Takata Tomomi The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Yagi Asami Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, 565-0871, Suita, Osaka, Japan aut NATIONALLICENCE 700 1- Terai Yoshito The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Ohmichi Masahide The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Ichimura Tomoyuki The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Sumi Toshiyuki The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Murata Hiromi The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Kanzaki Hideharu The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Nakai Hidekatsu The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Mandai Masaki The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Yoshino Kiyoshi The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Fujita Masami The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Kimura Tadashi The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Saito Junko The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Sobue Tomotaka Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, 565-0871, Suita, Osaka, Japan aut NATIONALLICENCE 700 1- Nishikawa Nobumichi Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, 951-8510, Chuo-ku, Niigata, Japan aut NATIONALLICENCE 700 1- Sekine Masayuki Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, 951-8510, Chuo-ku, Niigata, Japan aut NATIONALLICENCE 700 1- Enomoto Takayuki The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Horikoshi Yorihiko The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 700 1- Takagi Tetsu The Obstetrical Gynecological Society of Osaka, 4-4-3 Kawaramachi, 541-0048, Chuo-ku, Osaka, Japan aut NATIONALLICENCE 773 0- International Journal of Clinical Oncology Springer Japan 20/3(2015-06-01), 549-555 1341-9625 20:3<549 2015 20 10147