Evaluation of postoperative chemotherapy in patients with uterine carcinosarcoma: a retrospective survey of the Tohoku Gynecologic Cancer Unit

Verfasser / Beitragende:
[Ai Otsuki, Takeo Otsuki, Hideki Tokunaga, Hitoshi Niikura, Satoru Nagase, Takashi Sugiyama, Masafumi Toyoshima, Hiroki Utsunomiya, Yoshihito Yokoyama, Hideki Mizunuma, Naoki Sato, Yukihiro Terada, Tadahiro Shoji, Toru Sugiyama, Kenji Nakahara, Tsuyoshi Ohta, Hidekazu Yamada, Toru Tase, Hiroshi Nishiyama, Keiya Fujimori, Tadao Takano, Fumiaki Takahashi, Yoh Watanabe, Nobuo Yaegashi]
Ort, Verlag, Jahr:
2015
Enthalten in:
International Journal of Clinical Oncology, 20/3(2015-06-01), 574-578
Format:
Artikel (online)
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245 0 0 |a Evaluation of postoperative chemotherapy in patients with uterine carcinosarcoma: a retrospective survey of the Tohoku Gynecologic Cancer Unit  |h [Elektronische Daten]  |c [Ai Otsuki, Takeo Otsuki, Hideki Tokunaga, Hitoshi Niikura, Satoru Nagase, Takashi Sugiyama, Masafumi Toyoshima, Hiroki Utsunomiya, Yoshihito Yokoyama, Hideki Mizunuma, Naoki Sato, Yukihiro Terada, Tadahiro Shoji, Toru Sugiyama, Kenji Nakahara, Tsuyoshi Ohta, Hidekazu Yamada, Toru Tase, Hiroshi Nishiyama, Keiya Fujimori, Tadao Takano, Fumiaki Takahashi, Yoh Watanabe, Nobuo Yaegashi] 
520 3 |a Abstract : Background: The aim of this study was to evaluate prognostic factors including efficacy of postoperative chemotherapy in Japanese patients with uterine carcinosarcoma. Methods: We conducted a retrospective survey of seven medical facilities in the Tohoku Gynecologic Cancer Unit. Results: A total of 45 patients who had undergone hysterectomy and bilateral salpingo-oophorectomy were enrolled. No significant difference was observed in overall survival according to patient age (≤50years vs >50years) or retroperitoneal lymphadenectomy (performed vs. not performed). However, the International Federation of Gynecology and Obstetrics stage (stage I/II vs stage III/IV) and postoperative chemotherapy (provided vs not provided) were significant prognostic factors in both univariate and multivariate analyses for the 25-month median follow-up period. Conclusions: Our results revealed that postoperative chemotherapy should be considered for all uterine carcinosarcoma stages in Japanese patients. 
540 |a Japan Society of Clinical Oncology, 2014 
690 7 |a Uterine carcinosarcoma  |2 nationallicence 
690 7 |a Prognostic factor  |2 nationallicence 
690 7 |a Chemotherapy  |2 nationallicence 
690 7 |a Retrospective study  |2 nationallicence 
700 1 |a Otsuki  |D Ai  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Otsuki  |D Takeo  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Tokunaga  |D Hideki  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Niikura  |D Hitoshi  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Nagase  |D Satoru  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Sugiyama  |D Takashi  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Toyoshima  |D Masafumi  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Utsunomiya  |D Hiroki  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Yokoyama  |D Yoshihito  |u Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan  |4 aut 
700 1 |a Mizunuma  |D Hideki  |u Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan  |4 aut 
700 1 |a Sato  |D Naoki  |u Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan  |4 aut 
700 1 |a Terada  |D Yukihiro  |u Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan  |4 aut 
700 1 |a Shoji  |D Tadahiro  |u Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan  |4 aut 
700 1 |a Sugiyama  |D Toru  |u Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan  |4 aut 
700 1 |a Nakahara  |D Kenji  |u Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Japan  |4 aut 
700 1 |a Ohta  |D Tsuyoshi  |u Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Japan  |4 aut 
700 1 |a Yamada  |D Hidekazu  |u Department of Gynecology, Miyagi Cancer Center, Sendai, Japan  |4 aut 
700 1 |a Tase  |D Toru  |u Department of Gynecology, Miyagi Cancer Center, Sendai, Japan  |4 aut 
700 1 |a Nishiyama  |D Hiroshi  |u Department of Obstetrics and Gynecology, Fukushima Medical University, Fukushima, Japan  |4 aut 
700 1 |a Fujimori  |D Keiya  |u Department of Obstetrics and Gynecology, Fukushima Medical University, Fukushima, Japan  |4 aut 
700 1 |a Takano  |D Tadao  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Takahashi  |D Fumiaki  |u Department of Clinical Research Network, Clinical Research, Innovation and Education Center, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Miyagi, Japan  |4 aut 
700 1 |a Watanabe  |D Yoh  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
700 1 |a Yaegashi  |D Nobuo  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
773 0 |t International Journal of Clinical Oncology  |d Springer Japan  |g 20/3(2015-06-01), 574-578  |x 1341-9625  |q 20:3<574  |1 2015  |2 20  |o 10147 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Otsuki  |D Ai  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Otsuki  |D Takeo  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tokunaga  |D Hideki  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Niikura  |D Hitoshi  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nagase  |D Satoru  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sugiyama  |D Takashi  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Toyoshima  |D Masafumi  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Utsunomiya  |D Hiroki  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yokoyama  |D Yoshihito  |u Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Mizunuma  |D Hideki  |u Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sato  |D Naoki  |u Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Terada  |D Yukihiro  |u Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shoji  |D Tadahiro  |u Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sugiyama  |D Toru  |u Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nakahara  |D Kenji  |u Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ohta  |D Tsuyoshi  |u Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yamada  |D Hidekazu  |u Department of Gynecology, Miyagi Cancer Center, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tase  |D Toru  |u Department of Gynecology, Miyagi Cancer Center, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nishiyama  |D Hiroshi  |u Department of Obstetrics and Gynecology, Fukushima Medical University, Fukushima, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fujimori  |D Keiya  |u Department of Obstetrics and Gynecology, Fukushima Medical University, Fukushima, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Takano  |D Tadao  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Takahashi  |D Fumiaki  |u Department of Clinical Research Network, Clinical Research, Innovation and Education Center, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Miyagi, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Watanabe  |D Yoh  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yaegashi  |D Nobuo  |u Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t International Journal of Clinical Oncology  |d Springer Japan  |g 20/3(2015-06-01), 574-578  |x 1341-9625  |q 20:3<574  |1 2015  |2 20  |o 10147