caa a22 4500 605490953 CHVBK 20210128100507.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10147-014-0732-0 doi (NATIONALLICENCE)springer-10.1007/s10147-014-0732-0 Evaluation of postoperative chemotherapy in patients with uterine carcinosarcoma: a retrospective survey of the Tohoku Gynecologic Cancer Unit [Elektronische Daten] [Ai Otsuki, Takeo Otsuki, Hideki Tokunaga, Hitoshi Niikura, Satoru Nagase, Takashi Sugiyama, Masafumi Toyoshima, Hiroki Utsunomiya, Yoshihito Yokoyama, Hideki Mizunuma, Naoki Sato, Yukihiro Terada, Tadahiro Shoji, Toru Sugiyama, Kenji Nakahara, Tsuyoshi Ohta, Hidekazu Yamada, Toru Tase, Hiroshi Nishiyama, Keiya Fujimori, Tadao Takano, Fumiaki Takahashi, Yoh Watanabe, Nobuo Yaegashi] Abstract : Background: The aim of this study was to evaluate prognostic factors including efficacy of postoperative chemotherapy in Japanese patients with uterine carcinosarcoma. Methods: We conducted a retrospective survey of seven medical facilities in the Tohoku Gynecologic Cancer Unit. Results: A total of 45 patients who had undergone hysterectomy and bilateral salpingo-oophorectomy were enrolled. No significant difference was observed in overall survival according to patient age (≤50years vs >50years) or retroperitoneal lymphadenectomy (performed vs. not performed). However, the International Federation of Gynecology and Obstetrics stage (stage I/II vs stage III/IV) and postoperative chemotherapy (provided vs not provided) were significant prognostic factors in both univariate and multivariate analyses for the 25-month median follow-up period. Conclusions: Our results revealed that postoperative chemotherapy should be considered for all uterine carcinosarcoma stages in Japanese patients. Japan Society of Clinical Oncology, 2014 Uterine carcinosarcoma nationallicence Prognostic factor nationallicence Chemotherapy nationallicence Retrospective study nationallicence Otsuki Ai Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Otsuki Takeo Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Tokunaga Hideki Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Niikura Hitoshi Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Nagase Satoru Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Sugiyama Takashi Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Toyoshima Masafumi Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Utsunomiya Hiroki Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Yokoyama Yoshihito Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan aut Mizunuma Hideki Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan aut Sato Naoki Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan aut Terada Yukihiro Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan aut Shoji Tadahiro Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan aut Sugiyama Toru Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan aut Nakahara Kenji Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Japan aut Ohta Tsuyoshi Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Japan aut Yamada Hidekazu Department of Gynecology, Miyagi Cancer Center, Sendai, Japan aut Tase Toru Department of Gynecology, Miyagi Cancer Center, Sendai, Japan aut Nishiyama Hiroshi Department of Obstetrics and Gynecology, Fukushima Medical University, Fukushima, Japan aut Fujimori Keiya Department of Obstetrics and Gynecology, Fukushima Medical University, Fukushima, Japan aut Takano Tadao Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Takahashi Fumiaki Department of Clinical Research Network, Clinical Research, Innovation and Education Center, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Miyagi, Japan aut Watanabe Yoh Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut Yaegashi Nobuo Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut International Journal of Clinical Oncology Springer Japan 20/3(2015-06-01), 574-578 1341-9625 20:3<574 2015 20 10147 https://doi.org/10.1007/s10147-014-0732-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10147-014-0732-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Otsuki Ai Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Otsuki Takeo Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Tokunaga Hideki Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Niikura Hitoshi Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Nagase Satoru Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Sugiyama Takashi Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Toyoshima Masafumi Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Utsunomiya Hiroki Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Yokoyama Yoshihito Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan aut NATIONALLICENCE 700 1- Mizunuma Hideki Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan aut NATIONALLICENCE 700 1- Sato Naoki Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan aut NATIONALLICENCE 700 1- Terada Yukihiro Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan aut NATIONALLICENCE 700 1- Shoji Tadahiro Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan aut NATIONALLICENCE 700 1- Sugiyama Toru Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan aut NATIONALLICENCE 700 1- Nakahara Kenji Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Japan aut NATIONALLICENCE 700 1- Ohta Tsuyoshi Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Japan aut NATIONALLICENCE 700 1- Yamada Hidekazu Department of Gynecology, Miyagi Cancer Center, Sendai, Japan aut NATIONALLICENCE 700 1- Tase Toru Department of Gynecology, Miyagi Cancer Center, Sendai, Japan aut NATIONALLICENCE 700 1- Nishiyama Hiroshi Department of Obstetrics and Gynecology, Fukushima Medical University, Fukushima, Japan aut NATIONALLICENCE 700 1- Fujimori Keiya Department of Obstetrics and Gynecology, Fukushima Medical University, Fukushima, Japan aut NATIONALLICENCE 700 1- Takano Tadao Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Takahashi Fumiaki Department of Clinical Research Network, Clinical Research, Innovation and Education Center, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, 980-8574, Sendai, Miyagi, Japan aut NATIONALLICENCE 700 1- Watanabe Yoh Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 700 1- Yaegashi Nobuo Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan aut NATIONALLICENCE 773 0- International Journal of Clinical Oncology Springer Japan 20/3(2015-06-01), 574-578 1341-9625 20:3<574 2015 20 10147