Timing and characteristics of radiation pneumonitis after stereotactic body radiotherapy for peripherally located stage I lung cancer
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| 024 | 7 | 0 | |a 10.1007/s10147-014-0766-3 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10147-014-0766-3 | ||
| 245 | 0 | 0 | |a Timing and characteristics of radiation pneumonitis after stereotactic body radiotherapy for peripherally located stage I lung cancer |h [Elektronische Daten] |c [Ayae Kanemoto, Yasuo Matsumoto, Tadashi Sugita] |
| 520 | 3 | |a Background: This study was conducted to determine the timing and characteristics of radiation pneumonitis (RP) associated with stereotactic body radiotherapy (SBRT) for stage I lung cancer. Methods: Two hundred thirty-one patients treated with SBRT using 52Gy in 4 fractions were identified. Control rate, RP incidence rate, and predictive factors and timing of RP were evaluated retrospectively. Results: The 3-year overall survival and local control rates were 80.7 and 92.0%, respectively. The grade ≥2 RP rate was 13.0%; no grade 4-5 RP occurred. The most statistically significant predictive factor of grade ≥2 RP was V10. The median intervals to first graphical appearance were 4.2 and 2.5months for grade 1 and grade 2-3 RP, respectively. Median intervals to maximum radiological density change were 6.0 and 4.6months for grade 1 and grade 2-3 RP, respectively. A significantly different interval to first graphical appearance between grade 1 and grade 2-3 RP was observed; no significantly different interval to maximum radiological density change was noted. Conclusions: The first graphical appearance of grade ≥2 RP was earlier than that of grade 1 RP, although the timing of maximum radiological density change was not significantly different. | |
| 540 | |a Japan Society of Clinical Oncology, 2014 | ||
| 690 | 7 | |a Stage I lung cancer |2 nationallicence | |
| 690 | 7 | |a Stereotactic body radiotherapy |2 nationallicence | |
| 690 | 7 | |a Radiation pneumonitis |2 nationallicence | |
| 690 | 7 | |a Timing |2 nationallicence | |
| 690 | 7 | |a Predictive factor |2 nationallicence | |
| 700 | 1 | |a Kanemoto |D Ayae |u Department of Radiation Oncology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, 951-8566, Niigata, Japan |4 aut | |
| 700 | 1 | |a Matsumoto |D Yasuo |u Department of Radiation Oncology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, 951-8566, Niigata, Japan |4 aut | |
| 700 | 1 | |a Sugita |D Tadashi |u Department of Radiation Oncology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, 951-8566, Niigata, Japan |4 aut | |
| 773 | 0 | |t International Journal of Clinical Oncology |d Springer Japan |g 20/4(2015-08-01), 680-685 |x 1341-9625 |q 20:4<680 |1 2015 |2 20 |o 10147 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10147-014-0766-3 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10147-014-0766-3 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kanemoto |D Ayae |u Department of Radiation Oncology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, 951-8566, Niigata, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Matsumoto |D Yasuo |u Department of Radiation Oncology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, 951-8566, Niigata, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sugita |D Tadashi |u Department of Radiation Oncology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, 951-8566, Niigata, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t International Journal of Clinical Oncology |d Springer Japan |g 20/4(2015-08-01), 680-685 |x 1341-9625 |q 20:4<680 |1 2015 |2 20 |o 10147 | ||