caa a22 4500 605491313 CHVBK 20210128100509.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s10147-014-0781-4 doi (NATIONALLICENCE)springer-10.1007/s10147-014-0781-4 Treatment modalities for Māori and New Zealand European men with localised prostate cancer [Elektronische Daten] [Zuzana Obertová, Ross Lawrenson, Nina Scott, Michael Holmes, Charis Brown, Chunhuan Lao, Leanne Tyrie, Peter Gilling] Abstract : Objectives: To examine diagnostic and treatment pathways for Māori (the indigenous people of New Zealand [NZ]) and NZ European men with prostate cancer in order to identify causes of higher mortality rates for Māori men. Methods: All Māori men (150) diagnosed with prostate cancer in the Midland Cancer Network region between 2007 and 2010 were identified from the NZ Cancer Registry and frequency age-matched with three randomly sampled NZ European men. Clinical records of these men were searched for information on clinical stage at diagnosis, comorbidities, and type of treatment for localised disease. Results: The final cohort included 136 Māori and 400 NZ European men, of whom 97 Māori and 311 NZ European were diagnosed with localised prostate cancer. Māori men were twice as likely to be diagnosed with distant metastases compared with NZ European men (19.1 vs 9.8%). Māori men with localised disease were less likely to be treated with radical prostatectomy compared with NZ European men [RR 0.66 (95% CI 0.48, 0.90)]. Multivariate regression analysis adjusted for age, D'Amico risk strata, comorbidities, and socioeconomic deprivation showed that Māori men were more likely to be managed expectantly [RR 1.74 (95% CI 1.06, 2.57)]. Conclusion: Differences between Māori and NZ European men observed in the management of localised prostate cancer cannot be readily explained by patient characteristics, such as comorbidities or risk assessment at diagnosis. Poorer outcomes for Māori men may not only be related to later stage at diagnosis but differences in treatment modalities may also be a factor. Japan Society of Clinical Oncology, 2015 Active surveillance nationallicence Ethnicity nationallicence Radical prostatectomy nationallicence Radiotherapy nationallicence Watchful waiting nationallicence Obertová Zuzana Waikato Clinical School, Peter Rothwell Academic Centre, University of Auckland, Private Bag 3200, 3240, Hamilton, New Zealand aut Lawrenson Ross Waikato Clinical School, Peter Rothwell Academic Centre, University of Auckland, Private Bag 3200, 3240, Hamilton, New Zealand aut Scott Nina Te Puna Oranga, Waikato District Health Board, Hamilton, New Zealand aut Holmes Michael Urology Department, Waikato Hospital, Hamilton, New Zealand aut Brown Charis Waikato Clinical School, Peter Rothwell Academic Centre, University of Auckland, Private Bag 3200, 3240, Hamilton, New Zealand aut Lao Chunhuan Waikato Clinical School, Peter Rothwell Academic Centre, University of Auckland, Private Bag 3200, 3240, Hamilton, New Zealand aut Tyrie Leanne Radiation Oncology, Waikato Hospital, Hamilton, New Zealand aut Gilling Peter Department of Surgery, University of Auckland, Auckland, New Zealand aut International Journal of Clinical Oncology Springer Japan 20/4(2015-08-01), 814-820 1341-9625 20:4<814 2015 20 10147 https://doi.org/10.1007/s10147-014-0781-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10147-014-0781-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Obertová Zuzana Waikato Clinical School, Peter Rothwell Academic Centre, University of Auckland, Private Bag 3200, 3240, Hamilton, New Zealand aut NATIONALLICENCE 700 1- Lawrenson Ross Waikato Clinical School, Peter Rothwell Academic Centre, University of Auckland, Private Bag 3200, 3240, Hamilton, New Zealand aut NATIONALLICENCE 700 1- Scott Nina Te Puna Oranga, Waikato District Health Board, Hamilton, New Zealand aut NATIONALLICENCE 700 1- Holmes Michael Urology Department, Waikato Hospital, Hamilton, New Zealand aut NATIONALLICENCE 700 1- Brown Charis Waikato Clinical School, Peter Rothwell Academic Centre, University of Auckland, Private Bag 3200, 3240, Hamilton, New Zealand aut NATIONALLICENCE 700 1- Lao Chunhuan Waikato Clinical School, Peter Rothwell Academic Centre, University of Auckland, Private Bag 3200, 3240, Hamilton, New Zealand aut NATIONALLICENCE 700 1- Tyrie Leanne Radiation Oncology, Waikato Hospital, Hamilton, New Zealand aut NATIONALLICENCE 700 1- Gilling Peter Department of Surgery, University of Auckland, Auckland, New Zealand aut NATIONALLICENCE 773 0- International Journal of Clinical Oncology Springer Japan 20/4(2015-08-01), 814-820 1341-9625 20:4<814 2015 20 10147